In many settings, tumor-associated inflammation, supported mainly by innate immune cells,
contributes to tumor growth. Initial innate activation triggers secretion of inflammatory …

Recent advances in cancer immunotherapy, particularly immune checkpoint blockade
therapy have dramatically changed the therapeutic strategy against advanced malignancies …

Inflammatory responses play decisive roles at different stages of tumor development,
including initiation, promotion, malignant conversion, invasion, and metastasis. Inflammation …

The immune system has crucial roles in cancer development and treatment. Whereas
adaptive immunity can prevent or constrain cancer through immunosurveillance, innate …

Innate and adaptive immune system cells play a major role in regulating the growth of
cancer. Although it is commonly thought that an immune response localized to the tumor will …

Tumour-promoting inflammation is considered one of the enabling characteristics of cancer
development. Chronic inflammatory disease increases the risk of some cancers, and strong …

Cancer development and its response to therapy are strongly influenced by innate and
adaptive immunity, which either promote or attenuate tumorigenesis and can have opposing …

Chronic inflammation increases the risk of several cancers, including gastric, colon, and
hepatic cancers. Conversely, tumors, similar to tissue injury, trigger an inflammatory …

Immunotherapy has revolutionized cancer treatment, but efficacy remains limited in most
clinical settings. Cancer is a systemic disease that induces many functional and …

It has been established that cancer can be promoted and/or exacerbated by inflammation
and infections. Indeed, chronic inflammation orchestrates a tumor-supporting …