Digoxin tissue concentrations and elimination kinetics were determined to explore possible
explanations of the age-related changes in response to digoxin in the rat. Digoxin …

A radioimmunoassay for serum digoxin concentration has been used to study the
interrelationships of circulating levels of the drug and various factors in the clinical setting in …

Abstract Walsh, FM, and Sode, Jonas: Significance of non-steady-state serum digoxin
concentrations. Am J Clin Pathol 63: 446–450, 1975. In order better to define the optimal …

Serum digoxin level was determined by radioimmunoassay in 76 elderly in-patients (age:
76.1+/-1.0) which were treated by digoxin without any evidence of toxicity. Digoxin levels …

Thirteen aged persons receiving digoxin until the time of death were examined by autopsy,
and digoxin concentrations were determined in samples from various tissues (the choroid …

In guinea‐pigs intravenously infused with digoxin, prior immunization using a digoxin‐
human serum albumin conjugate increased by 3‐and 2.4‐fold, respectively, the digoxin …

Cardiotoxicity remains a significant problem limiting the clinical usefulness of the cardiac
glycosides. Many recent studies have demonstrated that patients showing clear evidence of …

To investigate the basis for a clinically important digitalis-quinidine interaction that is
characterized by increases in serums digoxin concentrations when quinidine is …

Forty-seven patients who were being treated with digoxin in a daily dose range of 0.25 mg.
to 0.75 mg. were the study material. Thirty-two patients were toxic. Seven patients out of …

The reversal of digoxin effects by digoxin antibody (Ab) may be mediated by at least two
mechanisms. First, the Ab may simply decrease the concentration of free digoxin in the …