The influence of potassium deficiency on myocardial 3H-digoxin concentration in the mouse
was studied. Tritiated digoxin, 400 µg/kg, was injected intraperitoneally into mice, which …

A sensitive and selective high-performance liquid chromatographic-post column
derivatization (HPLC-PC) method was used to determine the digoxin levels in the sera of …

The criteria which a drug must fulfil before it can be said that it may be worthwhile making
regular plasma concentration measurements of that drug in monitoring therapy are …

Seven healthy volunteers received a single 1.0‐mg dose of intravenous digoxin in a drug‐
free control trial and again during concurrent therapy with therapeutic doses of quinidine …

ABSTRACT Gibson, Thomas P. and Antonio P. Quintanilla: The renal clearance of digoxin is
dependent upon the serum digoxin concentration. J. Pharmacol. Exp. Ther. 21 5: 681-684 …

Abstract 6 newborn and 6 adult sheep were treated intravenously with digoxin for 2 weeks
prior to sacrifice. Plasma and myocardial concentrations of digoxin were determined at …

The effect of diltiazem on digoxin serum concentration was evaluated in 9 patients who had
been treated chronically for heart disease with digoxin, 0.25 mg/day. The indications for …

Turnover rates of tritium-labeled digoxin in the blood serum were studied in dogs after
cardiopulmonary bypass. Two significant alterations in the turnover rates of digoxin were …

Blood samples and skeletal muscle biopsies (m. quadriceps femoris, vastus lateralis) were
taken from seven healthy subjects for analysis of serum and skeletal muscle digoxin …

Since Megges and Repke [1961] showed that acetylation of the hydroxyl groups in the
aglycone or the sugar side chain of the digitalis molecule results in a derivative with …