The formation of precise connections between neurons and their targets during
development is dependent on extracellular guidance cues that allow growing axons to …

Netrins are a family of proteins that direct cell and axon migration during development.
Three secreted netrins (netrin-1,-3 and-4) have been identified in mammals, in addition to …

Netrins are a family of secreted proteins that direct the migration of cells and axonal growth
cones during neural development. They are bifunctional cues, attracting some cell types and …

Named after the Sanskrit word netr, which means' one who guides', the netrin family of
secreted proteins provides migrational cues in the developing central nervous system …

Netrin-1 is a guidance cue that can trigger either attraction or repulsion effects on migrating
axons of neurons, depending on the repertoire of receptors available on the growth cone …

Netrins are secreted proteins that were first identified as guidance cues, directing cell and
axon migration during neural development. Subsequent findings have demonstrated that …

Netrins are secreted proteins that regulate axon guidance and neuronal migration. Deleted
in colorectal cancer (DCC) is a well-established netrin-1 receptor mediating attractive …

The proper regulation of temporal and spatial expression of the axon guidance cues and
their receptors is critical for the normal wiring of nervous system during development …

Axon guidance mechanisms are crucial to the development of an integrated nervous system.
One family of molecules that may be important in establishing axonal connectivity in …

During the development of the nervous system, neurons respond to the coordinated action
of a variety of attractive and repulsive signals from the embryonic environment. Netrins form …