We compared the effects of antigen (Ag) presentation by T cells and professional antigen‐
presenting cells (APC) on T cell proliferation, cytokine production and surface molecule …

These studies tested whether antigenic competition between T cells occurs. We generated
CD8+ T cell responses in H-2b mice against the dominant ovalbumin epitope SIINFEKL …

Nowadays there is compelling evidence for immunoregulation by T cells. Recently, we
showed that so-called 'anergic'T cells are not functionally inert but can act as regulatory cells …

One of the factors that may influence the cytokine secretion profile of a T cell is the antigen‐
presenting cell (APC). Since activated human T cells have been described to express major …

We here show that anergic T cells are active mediators of T cell suppression. In co‐culture
experiments, we found that anergic T cells, derived from established rat T cell clones and …

The purpose of this study was to determine whether the clonotypic specificity of the T cell
receptor influences the specificity of T cell‐mediated antigen presentation. We have …

Efficient peptide presentation by professional APC to naive and effector CD4 T cells in vitro
is limited to the first 1–2 days of culture, but is nonetheless optimum for effector expansion …

Professional APC play a central role in generating antiviral CD8+ CTL immunity. However,
the fate of such APC following interaction with these same CTL remains poorly understood …

B cells have been known for their ability to present antigens to T cells for almost 40 years.
However, the precise roles of B cell antigen presentation in various immune responses are …

Professional antigen-presenting cells (APCs) are capable of transporting self-antigens from
peripheral tissues to secondary lymphoid organs where they are presented to potentially …