Few studies have examined the association between smoking status (including former
smokers) at diagnosis and overall survival among cancer patients. We aimed to assess the …

Comprehensive studies on cancer patients with different smoking histories, including non-
smokers, former smokers, and current smokers, remain elusive. Therefore, we conducted a …

Omics-based studies have substantially contributed to the emergence and progress of
systems biology over the past decades. Each layer of omics data provides a unique …

Background Incidence and mortality of lung cancer have dramatically decreased during the
last decades, yet still approximately 160,000 deaths per year occurred in United States …

PURPOSE Approximately 10%-40% of patients with lung cancer report no history of tobacco
smoking (never-smokers). We analyzed whole-exome and RNA-sequencing data of 160 …

Background Tobacco smoking is responsible for over 90% of lung cancer cases, and yet the
precise molecular alterations induced by smoking in lung that develop into cancer and …

Lung squamous cell carcinoma (LUSC) is the most common histologic type of smoking-
related non-small cell lung cancer (NSCLC). However, there are no identified potential …

Purpose: Cigarette smoking is the major pathogenic factor for lung cancer. The precise
mechanisms of tobacco-related carcinogenesis and its effect on the genomic and …

Background Lung cancer is the worldwide leading cause of death from cancer. Tobacco
usage is the major pathogenic factor, but all lung cancers are not attributable to smoking …

Bladder cancer is one of the top five most prevalent cancers in the United States and a major
cause of cancer-related mortality worldwide. Meanwhile, tobacco smoking is a well …