Microbial synthesis of non-natural anthraquinone glucosides displaying superior antiproliferative properties

TTH Nguyen, RP Pandey, P Parajuli, JM Han, HJ Jung… - Molecules, 2018 - mdpi.com
Anthraquinones, naturally occurring bioactive compounds, have been reported to exhibit
various biological activities, including anti-inflammatory, antiviral, antimicrobial, and …

[PDF][PDF] Microbial transformation of bioactive anthraquinones–a review

S Sultan, NA Ghani, SAA Shah, NH Ismail… - … Biotechnol. Res. Asia, 2013 - researchgate.net
Anthraquinones, especially hydroxyanthraquinones, constitute one of the most ubiquitous
classes of naturally occurring phenolic compounds. The hydroxyl and aminoanthraquiones …

Efficient enzymatic systems for synthesis of novel α-mangostin glycosides exhibiting antibacterial activity against Gram-positive bacteria

TT Le, RP Pandey, RB Gurung, D Dhakal… - Applied microbiology and …, 2014 - Springer
Two enzymatic systems were developed for the efficient synthesis of glycoside products of α-
mangostin, a natural xanthonoid exhibiting anti-oxidant, antibacterial, anti-inflammatory, and …

Discovery and characterization of four glycosyltransferases involved in anthraquinone glycoside biosynthesis in Rubia yunnanensis

S Yi, T Kuang, Y Miao, Y Xu, Z Wang… - Organic Chemistry …, 2020 - pubs.rsc.org
Glycosylation, which is catalyzed by UDP-glycosyltransferases, represents one of the most
common modifications in plant secondary metabolites and plays significant roles in plant …

Microbial Transformation of Amino- and Hydroxyanthraquinones by Beauveria bassiana ATCC 7159

J Zhan, AAL Gunatilaka - Journal of natural products, 2006 - ACS Publications
Microbial biotransformation of four amino-and hydroxyanthraquinones catalyzed by
Beauveria bassiana ATCC 7159 has been studied. Incubation of 1, 2-diaminoanthraquinone …

Biocatalytic Synthesis of Non-Natural Monoterpene O-Glycosides Exhibiting Superior Antibacterial and Antinematodal Properties

P Bashyal, RP Pandey, SB Thapa, MK Kang, CJ Kim… - ACS …, 2019 - ACS Publications
A promiscuous Bacillus glycosyltransferase (YjiC) was explored for the enzymatic synthesis
of monoterpene O-glycosides in vitro and in vivo. YjiC converted seven monoterpenes into …

Microbial Biosynthesis of Chrysazin Derivatives in Recombinant Escherichia coli and Their Biological Activities

PB Poudel, D Dhakal, RT Magar, JK Sohng - Molecules, 2022 - mdpi.com
Anthraquinone and its derivatives show remarkable biological properties such as
anticancer, antibacterial, antifungal, and antiviral activities. Hence, anthraquinones …

Discovery of novel glycerolated quinazolinones from Streptomyces sp. MBT27

NV Machushynets, C Wu, SS Elsayed… - Journal of Industrial …, 2019 - academic.oup.com
Actinobacteria are a major source of novel bioactive natural products. A challenge in the
screening of these microorganisms lies in finding the favorable growth conditions for …

Microbial glycosylation of four free anthraquinones by Absidia coerulea

W Zhang, M Ye, J Zhan, Y Chen, D Guo - Biotechnology letters, 2004 - Springer
Absidia coerulea transformed four anthraquinones from rhubarb, chrysophanol, physcion,
emodin and aloe-emodin to their corresponding glycosylated metabolites. The structures of …

Synthesis of methylated anthranilate derivatives using engineered strains of Escherichia coli

HL Lee, SY Kim, EJ Kim, DY Han, BG Kim… - Journal of microbiology …, 2019 - koreascience.kr
Anthranilate derivatives have been used as flavoring and fragrant agents for a long time.
Recently, these compounds are gaining attention due to new biological functions including …