Analysing M. avium-macrophage interactions and establishing a long-term infection in a novel and realistic model of lung alveolar macrophages, Max Planck Institute …

SA Thantri Hewage Peiris - 2024 - pearl.plymouth.ac.uk
Mycobacterium avium Complex (MAC) are species of the non-tuberculous branch of the
Mycobacteria family that is responsible for the development of pulmonary lung disease in …

Experimental Reactivation of Pulmonary Mycobacterium avium Complex Infection in a Modified Cornell-Like Murine Model

SB Cha, BY Jeon, WS Kim, JS Kim, HM Kim, KW Kwon… - PloS one, 2015 - journals.plos.org
The latency and reactivation of Mycobacterium tuberculosis infection has been well studied.
However, there have been few studies of the latency and reactivation of Mycobacterium …

The role of biofilms, bacterial phenotypes, and innate immune response in Mycobacterium avium colonization to infection

C Weathered, K Pennington, P Escalante… - Journal of Theoretical …, 2022 - Elsevier
Mycobacterium avium complex (MAC), is known for colonizing and infecting humans
following inhalation of the bacteria. MAC pulmonary disease is notoriously difficult to treat …

Development of Human Cell-Based In Vitro Infection Models to Determine the Intracellular Survival of Mycobacterium avium

G Kilinç, KV Walburg, KLMC Franken… - Frontiers in cellular …, 2022 - frontiersin.org
The Mycobacterium avium (Mav) complex accounts for more than 80% of all pulmonary
diseases caused by non-tuberculous mycobacteria (NTM) infections, which have an …

Modelling the interactions between Mycobacterium tuberculosis and innate alveolar macrophages

C Lack - 2021 - wrap.warwick.ac.uk
Tuberculosis (TB) kills over one million people annually, ranking it the leading cause of
death from a single infectious agent. Generally a pulmonary infection, the primary route of …

Virulence and immune response induced by Mycobacterium avium complex strains in a model of progressive pulmonary tuberculosis and subcutaneous infection in …

M González-Pérez, L Mariño-Ramírez… - Infection and …, 2013 - Am Soc Microbiol
The genus Mycobacterium comprises more than 150 species, including important
pathogens for humans which cause major public health problems. The vast majority of …

A marmoset model for Mycobacterium avium complex pulmonary disease

J Peters, DJ Maselli, M Mangat, JJ Coalson… - Plos one, 2023 - journals.plos.org
Rationale Mycobacterium avium complex, is the most common nontuberculous
mycobacterial respiratory pathogen in humans. Disease mechanisms are poorly understood …

A rhesus macaque model of pulmonary nontuberculous mycobacterial disease

K Winthrop, A Rivera, F Engelmann, S Rose… - American journal of …, 2016 - atsjournals.org
In this study, we sought to develop a nonhuman primate model of pulmonary Mycobacterium
avium complex (MAC) disease. Blood and bronchoalveolar lavage fluid were collected from …

Chemokine Signaling Caused by Mycobacterium avium Biofilms in the Lung Airway Increases Bacterial Loads by Spatially Diverting Macrophages

C Weathered, K Pennington, P Escalante, E Pienaar - bioRxiv, 2022 - biorxiv.org
Mycobacterium avium Complex (MAC) are ubiquitous environmental biofilm-forming
microbes that can colonize and infect patient lungs. Incidence and prevalence of MAC …

Mycobacterium avium Infection in a C3HeB/FeJ Mouse Model

D Verma, M Stapleton, J Gadwa… - Frontiers in …, 2019 - frontiersin.org
Infections caused by Mycobacterium avium complex (MAC) species are increasing
worldwide, resulting in a serious public health problem. Patients with MAC lung disease face …