Hypoxia-inducible factor-1 (HIF-1) controls the expression of a number of genes such as
vascular endothelial growth factor and erythropoietin in low oxygen conditions. However, the …

Hypoxia-inducible factor 1 (HIF-1) controls the expression of most genes induced by hypoxic
conditions. Regulation of expression and activity of its inducible subunit, HIF-1α, involves …

Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that mediates cellular and
systemic homeostatic responses to reduced O2 availability in mammals, including …

The hypoxia-inducible factors 1α (HIF-1α) and 2α (HIF-2α) have extensive structural
homology and have been identified as key transcription factors responsible for gene …

Hypoxia-inducible factor 1 (HIF-1) binds to cis-acting hypoxia-response elements within the
erythropoietin, vascular endothelial growth factor, and other genes to activate transcription in …

Hypoxia-inducible factor-1 (HIF-1) regulates the transcription of many genes induced by low
oxygen conditions. Recent studies have demonstrated that non-hypoxic stimuli can also …

The transcription factor hypoxia inducible factor α‐subunit (HIFα) is pivotal in the cellular
response to the stress of hypoxia. Post‐translational modification of HIFα by hydroxylase …

Mammalian cells are able to sense oxygen and regulate a number of genes in response to
hypoxia. The transcription factor Hypoxia Inducible Factor-1 (HIF-1) was identified as an …

Hypoxia-Inducible Factor-1 (HIF-1) is a transcription factor which is activated by hypoxia and
involved in the adaptative response of the cell to oxygen deprivation. During hypoxic stress …

The hypoxia-inducible factor (HIF)-1α and the HIF-like factor (HLF) transcription factors are
regulated at multiple levels including protein stabilization, nuclear import, and activation of …