An MRI technique with high selectivity and sensitivity to the signal components in the
chemical shift range of methylene and methyl protons of fatty acids has been developed for …

Magnetic resonance (MR) methods are increasingly being used to investigate the
physiology of human muscle. Although MR imaging (MRI) reveals the morphology of …

PURPOSE: To prospectively determine the repeatability and variability of tibialis anterior
intramyocellular lipid (IMCL) quantifications performed by using 1.5-T hydrogen 1 (1H) …

Fat can be stored not only in adipose tissue but also in other tissues such as skeletal
muscle. Fat droplets accumulated in skeletal muscle [intramyocellular lipids (IMCLs)] can be …

It has been suggested that a decline in skeletal muscle oxidative capacity is a general
consequence of aging in humans. However, previous studies have not always controlled for …

Three different methods to determine intramyocellular lipid (IMCL) contents in human
skeletal muscle have been compared. 1H-magnetic resonance spectroscopy (MRS) was …

Trained subjects are characterized by enhanced levels of lipolytic and mitochondrial
enzymes, and, hence, a higher reliance on fat oxidation, especially during aerobic …

Abstract 1H‐MR spectroscopy (MRS) of intramyocellular lipids (IMCL) became particularly
important when it was recognized that IMCL levels are related to insulin sensitivity. While …

Background: Aging skeletal muscle is characterized not only by a reduction in size
(sarcopenia) and strength but also by an increase in fatty infiltration (myosteatosis). An …

In skeletal muscle that is structurally normal, 1H NMR T2 is heavily dependent on and
reflective of water mobility in the tissue. Water mobility, measured by its inverse, water …