Abstract Background/Aims Clinical trials of older adults are increasingly common, but risks of
serious adverse events (SAE) may vary. We describe the incidence of SAE in two …

BACKGROUND/OBJECTIVES High‐quality research provides an evidence base for optimal
practice care in clinical settings, yet, little is known about the nature and extent of …

Background Clinical trials are needed to study topics relevant to older adults with serious
illness. Investigators conducting clinical trials with this population are challenged by how to …

The profile of care homes has never been higher and not necessarily for the best reasons
[1]. The COVID-19 pandemic has had, and continues to have, a massive impact on care …

OBJECTIVE To assess factors associated with trial participation in the context of a low‐risk
intervention intended to reduce adverse drug events in recently hospitalized older adults …

Generating and translating high‐quality evidence is integral to providing safe and effective
medication management for residents of aged care homes. Residents are often under …

OVeRVIeW One in seven Medicare beneficiaries experienced an adverse event while
hospitalized in 2008. Of those, 31% of the adverse events were related to medications …

An effective clinical research effort in nursing homes to address prevention and treatment of
COVID‐19 faced overwhelming challenges. Under the Health Care Systems Research …

Randomised controlled trials provide the most rigorous test of efficacy and effectiveness for
interventions used in healthcare. They underpin much of clinical practice, yet older people …

As a method of research, pragmatic trials are recommended so as to generate results that
are applicable to real-world care. This intent is especially important for the millions of older …