Peptide based antimicrobials: Design strategies and therapeutic potential

PK Hazam, R Goyal, V Ramakrishnan - Progress in Biophysics and …, 2019 - Elsevier
Therapeutic activity of antibiotics is noteworthy, as they are used in the treatment of microbial
infections. Regardless of their utility, there has been a steep decrease in the number of drug …

[HTML][HTML] A new era of antibiotics: the clinical potential of antimicrobial peptides

K Browne, S Chakraborty, R Chen… - International journal of …, 2020 - mdpi.com
Antimicrobial resistance is a multifaceted crisis, imposing a serious threat to global health.
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …

Recent approaches in design of peptidomimetics for antimicrobial drug discovery research

S Lohan, G Singh Bisht - Mini reviews in medicinal chemistry, 2013 - ingentaconnect.com
Resistant pathogenic microbial strains are emerging at a rate that far exceeds the pace of
new anti-infective drug development. In order to combat resistance development, there is …

Identification and design of antimicrobial peptides for therapeutic applications

A Ahmad, E Ahmad, G Rabbani… - Current Protein and …, 2012 - ingentaconnect.com
Indiscriminate use of antibiotics has led to a rapid increase of antibiotic resistance among
microbes which has increased the need to develop novel antimicrobial agents to fight …

Designing improved active peptides for therapeutic approaches against infectious diseases

B Gomes, MT Augusto, MR Felício, A Hollmann… - Biotechnology …, 2018 - Elsevier
Infectious diseases are one of the main causes of human morbidity and mortality. In the last
few decades, pathogenic microorganisms' resistance to conventional drugs has been …

Antimicrobial peptides: a promising therapeutic strategy in tackling antimicrobial resistance

R Nuti, NS Goud, AP Saraswati… - Current medicinal …, 2017 - ingentaconnect.com
Background: Antimicrobial resistance (AMR) has posed a serious threat to global public
health and it requires immediate action, preferably long term. Current drug therapies have …

Mini review on antimicrobial peptides, sources, mechanism and recent applications

JK Boparai, PK Sharma - Protein and peptide letters, 2020 - ingentaconnect.com
Antimicrobial peptides in recent years have gained increased interest among scientists,
health professionals and the pharmaceutical companies owing to their therapeutic potential …

[HTML][HTML] Lights and shadows on the therapeutic use of antimicrobial peptides

D Bellotti, M Remelli - Molecules, 2022 - mdpi.com
The emergence of antimicrobial-resistant infections is still a major concern for public health
worldwide. The number of pathogenic microorganisms capable of resisting common …

Peptide therapeutics versus superbugs: highlight on current research and advancements

K Nagarajan, SK Marimuthu, S Palanisamy… - International Journal of …, 2018 - Springer
Antibiotics have saved several millions of lives, but its persistent use of antibiotics in the
treatment of various infections, whether bacterial, fungal, viral or parasitic has lead to the …

Peptide‐based antibiotics: A potential answer to raging antimicrobial resistance

A Mor - Drug Development Research, 2000 - Wiley Online Library
Antibiotic resistance is an increasing problem worldwide. The emergence and spread of
multidrug‐resistant bacteria leads to treatment failure and is associated with severe …