Fatigue in multiple sclerosis: definition, pathophysiology and treatment

LB Krupp - CNS drugs, 2003 - Springer
Fatigue is a common disabling symptom of multiple sclerosis (MS). It is often considered a
state of exhaustion distinct from depressed mood or physical weakness. Fatigue can be …

Multiple sclerosis-associated fatigue

LB Krupp, DJ Serafin… - Expert review of …, 2010 - Taylor & Francis
Fatigue is an extremely prevalent issue for multiple sclerosis (MS) patients. Fatigue can
affect quality of life, depression, anxiety, motor function and sleep patterns. There are a …

Fatigue in multiple sclerosis–insights into evaluation and management

SS Ayache, MA Chalah - Neurophysiologie Clinique/Clinical …, 2017 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system, characterized by the accumulation of numerous neurological …

Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis: a randomised, placebo-controlled, crossover, double-blind trial

B Nourbakhsh, N Revirajan, B Morris… - The Lancet …, 2021 - thelancet.com
Background Methylphenidate, modafinil, and amantadine are commonly prescribed
medications for alleviating fatigue in multiple sclerosis; however, the evidence supporting …

Fatigue in multiple sclerosis—a brief review

I Induruwa, CS Constantinescu, B Gran - Journal of the neurological …, 2012 - Elsevier
Fatigue is the most common and debilitating symptom in multiple sclerosis (MS) and is
believed to be distinctly different from fatigue seen in other chronic conditions. It can affect a …

Pharmacological treatments for fatigue in patients with multiple sclerosis: a systematic review and meta-analysis

T Yang, L Wang, X Deng, G Yu - Journal of the neurological sciences, 2017 - Elsevier
Background Multiple sclerosis (MS) is a chronic immune-mediated inflammatory disease.
Fatigue is the most common symptom of MS patients, affecting> 80% subjects. Medical …

Pathophysiology, assessment and management of multiple sclerosis fatigue: an update

M Rottoli, S La Gioia, B Frigeni… - Expert review of …, 2017 - Taylor & Francis
Introduction: Fatigue is one of the most common symptoms associated with multiple
sclerosis, affecting almost 80% of patients with 55% of them reporting it as one of the worst …

Fatigue associated with multiple sclerosis: diagnosis, impact and management

R Bakshi - Multiple Sclerosis Journal, 2003 - journals.sagepub.com
In patients with multiple sclerosis (MS) fatigue is the most common symptom and one of the
most disabling features. A s many as 40% have described it as the single most disabling …

[HTML][HTML] Fatigue management in multiple sclerosis

C Tur - Current treatment options in neurology, 2016 - Springer
Opinion statement Multiple sclerosis (MS) is an inflammatory-demyelinating disease of the
central nervous system that may entail severe levels of disability in the long term. However …

[HTML][HTML] Fatigue in multiple sclerosis: misconceptions and future research directions

T Rudroff, JH Kindred, NB Ketelhut - Frontiers in neurology, 2016 - frontiersin.org
Fatigue is one of the most disabling side effects in people with multiple sclerosis. While this
fact is well known, there has been a remarkable lack of progress in determining the …