Background Fatigue is a multifactorial symptom frequently reported by multiple sclerosis
(MS) patients. To date, the pathophysiology of MS fatigue remains poorly understood and …

Fatigue is common in people with multiple sclerosis (MS) and symptoms of fatigue are often
reported as the most debilitating symptoms of the disease. However, there are few reports of …

Fatigue is a frequent and disabling symptom in patients with multiple sclerosis (MS), but it is
difficult to define and measure. Today, MS-related fatigue is not fully understood, and …

Fatigue is a frequent and debilitating symptom of multiple sclerosis (MS) with rates ranging
anywhere from 53 to 90%. Despite its high prevalence and grave impact on overall …

Fatigue is a feature of several chronic diseases of the central and peripheral nervous
system. The pathophysiology of central fatigue is complex and often not well-defined. In …

Objective: To reassess the effect of modafinil, a wakefulness-promoting artificial
psychostimulant, on fatigue and neuropsychological measures in patients with multiple …

Fatigue and depression are common conditions diagnosed in people with multiple sclerosis
(MS). Fatigue defined as subjective lack of physical and/or mental energy is present in 35 …

Fatigue is a very common symptom of multiple sclerosis (MS). Theoretically, fatigue may be
related to neuromodulation by soluble products of the autoimmune process or by disruption …

Background Studies in multiple sclerosis (MS) report conflicting conclusions regarding
fatigue and cognition, which may partly be due to the use of small sample sizes and frequent …

Objective To determine the relative efficacy of amantadine, pemoline, and placebo in
treatment of multiple sclerosis (MS)-related fatigue. Background Fatigue is a complication of …