Lipid-induced colonic hypersensitivity in the irritable bowel syndrome: the role of bowel habit, sex, and psychologic factors

M Simrén, H Abrahamsson, ES Björnsson - Clinical Gastroenterology and …, 2007 - Elsevier
Background & Aims: Duodenal lipid infusion increases colonic hypersensitivity in irritable
bowel syndrome (IBS). Whether this is affected by bowel habit, psychologic factors, or sex is …

Nutrient‐dependent enhancement of rectal sensitivity in irritable bowel syndrome (IBS)

M Simrén, P Agerforz, ES Björnsson… - …, 2007 - Wiley Online Library
Food‐related gastrointestinal symptoms are common in irritable bowel syndrome (IBS), but
the mechanisms behind this are unclear. Enhanced colorectal sensitivity after duodenal lipid …

An exaggerated sensory component of the gastrocolonic response in patients with irritable bowel syndrome

M Simren, H Abrahamsson, ES Björnsson - Gut, 2001 - gut.bmj.com
BACKGROUND/AIMS Visceral hypersensitivity is a feature of the irritable bowel syndrome
(IBS). Postprandial symptoms are common in these patients. The effects of nutrients on …

Visceral sensitivity and symptoms in patients with constipation-or diarrhea-predominant irritable bowel syndrome (IBS): effect of a low-fat intraduodenal infusion

MP Caldarella, A Milano, F Laterza… - Official journal of the …, 2005 - journals.lww.com
BACKGROUND Visceral hypersensitivity is common in Irritable Bowel Syndrome (IBS)
patients, and symptoms exacerbate postprandially. Yet the effects of nutrients on visceral …

Lipid‐induced colonic hypersensitivity in irritable bowel syndrome: the role of 5‐HT3 receptors

M Simren, L Simms, D D'souza… - Alimentary …, 2003 - Wiley Online Library
Background: Irritable bowel syndrome patients demonstrate colonic hypersensitivity after
duodenal lipid infusion. Aim: To investigate the role of 5‐hydroxytryptamine‐3 (5‐HT3) …

Treatment with hypnotherapy reduces the sensory and motor component of the gastrocolonic response in irritable bowel syndrome

M Simrén, G Ringström, ES Björnsson… - Psychosomatic …, 2004 - journals.lww.com
Objective Postprandial symptoms in irritable bowel syndrome are common and relate to an
exaggerated motor and sensory component of the gastrocolonic response. We investigated …

Intrarectal injection of glycerol induces hypersensitivity to rectal distension in healthy subjects without modifying rectal compliance

M Bouin, M Delvaux, C Blanc, E Lagier… - European journal of …, 2001 - journals.lww.com
Background Rectal sensory thresholds are lowered in patients with irritable bowel syndrome
(IBS), reflecting visceral hyperlagesia, which might be related to subclinical inflammation …

Intracolonic injection of glycerol: a model for abdominal pain in irritable bowel syndrome?

D Louvel, M Delvaux, G Staumont, F Camman… - Gastroenterology, 1996 - Elsevier
BACKGROUND & AIMS: Abdominal pain is the main symptom in patients with irritable bowel
syndrome (IBS). Glycerol is an irritant of colonic mucosa. The aim of this study was to …

Visceral hypersensitivity following cold water intake in subjects with irritable bowel syndrome

XL Zuo, YQ Li, L Shi, GP Lv, RG Kuang, XF Lu… - Journal of …, 2006 - Springer
Background Visceral hypersensitivity has been shown to be present in irritable bowel
syndrome (IBS). This study sought to investigate rectal sensitivity and abdominal symptoms …

Altered rectal perception in irritable bowel syndrome is associated with symptom severity

I Posserud, A Syrous, L Lindström, J Tack… - Gastroenterology, 2007 - Elsevier
Background & Aims: Diverging results exist regarding the connection between altered
visceral perception and gastrointestinal (GI) symptoms, as well as the effects of …