[HTML][HTML] DAP‐kinase is a Ca2+/calmodulin‐dependent, cytoskeletal‐associated protein kinase, with cell death‐inducing functions that depend on its catalytic activity
O Cohen, E Feinstein, A Kimchi - The EMBO journal, 1997 - embopress.org
DAP‐kinase was initially identified as a gene whose anti‐sense‐mediated reduced
expression protected HeLa cells from interferon‐γ‐induced programmed cell death. It was …
expression protected HeLa cells from interferon‐γ‐induced programmed cell death. It was …
DAP-kinase: from functional gene cloning to establishment of its role in apoptosis and cancer
O Cohen, A Kimchi - Cell Death & Differentiation, 2001 - nature.com
DAP-kinase is a pro-apoptotic Ca 2+ calmodulin-regulated serine/threonine kinase that
participates in a wide array of apoptotic systems initiated by interferon-γ, TNF-α, activated …
participates in a wide array of apoptotic systems initiated by interferon-γ, TNF-α, activated …
The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases
G Shohat, G Shani, M Eisenstein, A Kimchi - Biochimica et Biophysica Acta …, 2002 - Elsevier
DAP-kinase (DAPk) is a Ca2+/calmodulin (CaM)-regulated Ser/Thr kinase that functions as
a positive mediator of programmed cell death. It associates with actin microfilament and has …
a positive mediator of programmed cell death. It associates with actin microfilament and has …
Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase
Death-associated protein kinase (DAP kinase) is a proapoptotic, calcium/calmodulin-
dependent serine/threonine kinase. Here, we report that DAP kinase phosphorylates the …
dependent serine/threonine kinase. Here, we report that DAP kinase phosphorylates the …
DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals
Death-associated protein kinase (DAP-kinase) is a calcium/calmodulin-dependent
serine/threonine kinase, and participates in various apoptosis systems. However, its …
serine/threonine kinase, and participates in various apoptosis systems. However, its …
DAP-kinase-mediated morphological changes are localization dependent and involve myosin-II phosphorylation
S Bialik, AR Bresnick, A Kimchi - Cell Death & Differentiation, 2004 - nature.com
DAP-kinase (DAPk) is a Ser/Thr kinase that regulates cytoplasmic changes associated with
programmed cell death. It is shown here that a GFP–DAPk fusion, which partially localized to …
programmed cell death. It is shown here that a GFP–DAPk fusion, which partially localized to …
Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity
T Kawai, F Nomura, K Hoshino, NG Copeland… - Oncogene, 1999 - nature.com
We have identified and characterized a new calcium/calmodulin (Ca 2+/CaM) dependent
protein kinase termed death-associated protein kinase 2 (DAPK2) that contains an N …
protein kinase termed death-associated protein kinase 2 (DAPK2) that contains an N …
DAP kinase links the control of apoptosis to metastasis
B Inbal, O Cohen, S Polak-Charcon, J Kopolovic… - Nature, 1997 - nature.com
DAP kinase is a new type of calcium/calmodulin-dependent enzyme that phosphorylates
serine/threonine residues on proteins. Its structure contains ankyrin repeats and the …
serine/threonine residues on proteins. Its structure contains ankyrin repeats and the …
A functional genetic screen identifies regions at the C-terminal tail and death-domain of death-associated protein kinase that are critical for its proapoptotic activity
T Raveh, H Berissi, M Eisenstein… - Proceedings of the …, 2000 - National Acad Sciences
Death-associated protein kinase (DAP-kinase) is a Ca+ 2/calmodulin-regulated
serine/threonine kinase with a multidomain structure that participates in apoptosis induced …
serine/threonine kinase with a multidomain structure that participates in apoptosis induced …
DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene
JL Kissil, E Feinstein, O Cohen, PA Jones, YC Tsai… - Oncogene, 1997 - nature.com
DAP-kinase is a novel calmodulin dependent serine/threonine kinase that carries ankyrin
repeats and the death domain. It was recently isolated, by a functional selection approach of …
repeats and the death domain. It was recently isolated, by a functional selection approach of …
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