Results The seropositive rate of Helicobacter pylori (95/120 vs. 134/238, OR: 2.95, 95% CI
1.77-4.91), habitual smoking (67/120 vs. 82/238, OR: 2.40, 95% CI 1.54-3.77) and blood …

Background. The host genetic factors that determine the clinical outcomes for Helicobacter
pylori‐infected individuals remain unclear. Aims. To elucidate the relations among …

Introduction: Helicobacter pylori infection is associated with gastritis, peptic ulcer disease
and gastric carcinoma. The severity of damage is determined by the interplay between …

It is well known that the risk of development of gastric cancer (GC) in Helicobacter pylori-
infected patients depends on several factors. Thus, the aim of this study was to investigate …

OBJECTIVES The association between interleukin-1 polymorphisms, H. pylori and
increased gastric cancer risk remains controversial. AIMS To compare the prevalence of …

Background: Previous studies imply that IL-1 and IL-8 gene variations may play a crucial
role in the genetic predisposition to different gastric disorders upon H. pylori infection …

Background & Aims: Although epidemiological studies suggest that interleukin (IL)-1 genetic
polymorphisms are involved in Helicobacter pylori–related gastric carcinogenesis, the data …

Abstract Background and Aim: Helicobacter pylori is a major cause of chronic gastritis and
peptic ulcer disease and a definite carcinogen for gastric adenocarcinoma. However, the …

Abstract Background Interkeukin-1 (IL-1) gene cluster polymorphisms that are thought to
enhance the production of IL-1β are associated with an increased risk of gastric cancer. To …

Gastric carcinogenesis is a complex, multistep process, which may be influenced by many
factors and is the second most common type of malignancy and the second most-common …