Acid-sensing ion channels (ASICs) are expressed in various sensory and central neurons.
The functional role of these channels remains elusive. Complex subunit combinations and …

Publisher Summary This chapter discusses the structure of acid sensing ionic channels
(ASICs), their response profiles to acid, localization in a subset of sensory neurons, possible …

Proton receptors of the acid-sensing ion channel (ASIC) family are expressed in sensory
neurons and thus could play a critical role in the detection of noxious acidosis. To …

Acid‐sensing ion channels (ASICs) are proton‐gated cation channels that play important
roles in the CNS including synaptic plasticity and acidosis‐mediated neuronal injury …

Acid-sensing ion channels (ASICs) are activated by extracellular protons and are involved in
neurotransmission in the central nervous system, in pain perception, as well as in …

The mammalian nervous system expresses proton-gated ion channels known as acid-
sensing ion channels (ASICs). Depending on their location and specialization some …

Acid-sensing ion channels (ASICs) are a new and expanding family of proton-gated cation
(Na+/Ca 2+) channels that are widely expressed in sensory neurons and the central nervous …

Acid-sensing ion channels (ASICs) are sodium channels gated by extracellular protons.
ASIC1a channels possess intersubunit Cl−-binding sites in the extracellular domain, which …

Acid-sensing ion channels (ASICs) are Na+-permeable ion channels activated by protons
and predominantly expressed in the nervous system. ASICs act as pH sensors leading to …

Acid-sensing ion channels (ASICs) are a group of trimeric cation permeable channels gated
by extracellular protons that are mainly expressed in the nervous system. Despite the …