Immunocytochemical evidence for phorbol ester-induced directional translocations of protein kinase C in HL60, K562, CHO, and E7SKS cells: possible role in …
PR Girard, VL Stevens, PJ Blackshear, AH Merrill Jr… - Cancer research, 1987 - AACR
The effects of phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) on the directions of
protein kinase C (PKC) translocation in two leukemic cell lines (HL60 and K562) and two …
protein kinase C (PKC) translocation in two leukemic cell lines (HL60 and K562) and two …
Immunocytochemical evidence for phorbol ester-induced protein kinase C translocation in HL60 cells
M Shoji, PR Girard, GJ Mazzei, WR Vogler… - … and biophysical research …, 1986 - Elsevier
The ability of tumor promoting 12-O-tetradecanoylphorbol-13-acetate (TPA) to redistribute
protein kinase C in human promyelocytic leukemic HL60 cells was investigated. It was found …
protein kinase C in human promyelocytic leukemic HL60 cells was investigated. It was found …
Temporal changes in intracellular distribution of protein kinase C during differentiation of human leukemia HL60 cells induced by phorbol ester
Z Kiss, E Deli, JF Kuo - FEBS letters, 1988 - Wiley Online Library
Immunocytochemical methods were used to study protein kinase C (PKC) distribution in
HL60 cells during the entire course of 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) …
HL60 cells during the entire course of 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) …
Phorbol ester-induced alteration of differentiation and proliferation in human hematopoietic tumor cell lines: relationship to the presence and subcellular distribution of …
K Forsbeck, K Nilsson, A Hansson, G Skoglund… - Cancer research, 1985 - AACR
The intracellular translocation of protein kinase C (PKC) from the soluble to the membranous
fraction has been shown previously to correlate with biological activity of phorbol esters in …
fraction has been shown previously to correlate with biological activity of phorbol esters in …
Effects of phorbol ester on translocation and down-regulation of protein kinase C and phosphorylation of endogenous proteins in human acute myeloid leukemia cell …
M Shoji, PR Girard, PA Charp, HP Koeffler, WR Vogler… - Cancer research, 1987 - AACR
O-Tetradecanoylphorbol-13-acetate (TPA) induced decreases in the catalytic activity and
immunoreactivity of protein kinase C (PK-C) in the soluble fraction, accompanied by …
immunoreactivity of protein kinase C (PK-C) in the soluble fraction, accompanied by …
Phorbol esters induce both intracellular translocation and down-regulation of protein kinase C in MCF-7 cells
JM Darbon, M Issandon, F Delassus… - … and biophysical research …, 1986 - Elsevier
Exposure of MCF-7 human breast cancer cells to phorbol ester 12-O-tetradecanoyl-13-
acetate (TPA) results in a complete inhibition of cell proliferation. We investigated the effects …
acetate (TPA) results in a complete inhibition of cell proliferation. We investigated the effects …
Phorbol ester-mediated association of protein kinase C to the nuclear fraction in NIH 3T3 cells
TP Thomas, HS Talwar, WB Anderson - Cancer research, 1988 - AACR
Abstract Treatment of intact NIH 3T3 cells with 12-O-tetradecanoylphorbol-13-acetate (TPA)
causes a rapid redistribution (stabilization) of protein kinase C to the particulate fraction. Part …
causes a rapid redistribution (stabilization) of protein kinase C to the particulate fraction. Part …
Decreased expression of type II protein kinase C in HL-60 variant cells resistant to induction of cell differentiation by phorbol diester
M Nishikawa, F Komada, Y Uemura, H Hidaka… - Cancer Research, 1990 - AACR
To evaluate the molecular basis for susceptibility of the cell differentiation induced by 12-O-
tetradecanoylphorbol-13-acetate (TPA), we examined biochemical activities and expression …
tetradecanoylphorbol-13-acetate (TPA), we examined biochemical activities and expression …
Rapid microassay for protein kinase C translocation in Swiss 3T3 cells
Revised Manuscript Received October 27, 1986 abstract: The Ca2+/phosphatidylserine-
stimulated protein kinase C (PKC) appears to exist as interconvertible inactive, soluble and …
stimulated protein kinase C (PKC) appears to exist as interconvertible inactive, soluble and …
Type 3 protein kinase C localization to the nuclear envelope of phorbol ester-treated NIH 3T3 cells.
KL Leach, EA Powers, VA Ruff, S Jaken… - The Journal of cell …, 1989 - rupress.org
We have examined the immunocytochemical localization of protein kinase C (PKC) in NIH
3T3 cells using mAbs that recognize Type 3 PKC. In control cells, the immunofluorescent …
3T3 cells using mAbs that recognize Type 3 PKC. In control cells, the immunofluorescent …