Atomic vacancies-engineered ultrathin trimetallic nanozyme with anti-inflammation and antitumor performances for intestinal disease treatment

Y Wang, X Dai, L Wu, H Xiang, Y Chen, R Zhang - Biomaterials, 2023 - Elsevier
Colitis-associated colorectal cancer, which represents a highly aggressive subtypes of
colorectal cancer, requires concurrent antitumor and anti-inflammation therapies in clinic …

Rapid synthesis of trimetallic nanozyme for sustainable cascaded catalytic therapy via tumor microenvironment remodulation

X Jia, J Wang, E Wang - Advanced Materials, 2024 - Wiley Online Library
Tumor microenvironment (TME)‐responsive nanozyme‐catalyzed cancer therapy shows
great potential due to its specificity and efficiency. However, breaking the self‐adaption of …

Transition metal‐based therapies for inflammatory diseases

Y Song, Q You, X Chen - Advanced Materials, 2023 - Wiley Online Library
Inflammatory disease (ID) is a general term that covers all diseases in which chronic
inflammation performs as the major manifestation of pathogenesis. Traditional therapies …

Ultrasmall Cu2O@His Nanozymes with RONS Scavenging Capability for Anti-inflammatory Therapy

S Li, Z Chen, M Wang, F Yang, S Zhang… - … Applied Materials & …, 2024 - ACS Publications
High concentrations of reactive oxygen and nitrogen species (RONS) are key characteristics
of inflammatory sites. Scavenging RONS at the site of inflammation is an effective …

Heterostructure nanozymes with sustainable tumor microenvironment regulation and reinforced hyperthermia-responsive catalytic activities for orchestrated …

X Zhang, X Li, M Fu, JO Machuki, W Wang, L Wu… - Chemical Engineering …, 2024 - Elsevier
Catalytic therapy employing nanozymes has evoked extensive exploration as a promising
regimen for cancer theranostics, with specific reactivity in response to tumor …

Construction of pH‐Dependent Nanozymes with Oxygen Vacancies as the High‐Efficient Reactive Oxygen Species Scavenger for Oral‐Administrated Anti …

N Zhao, FE Yang, CY Zhao, SW Lv… - Advanced …, 2021 - Wiley Online Library
It is of great significance to eliminate excessive reactive oxygen species (ROS) for treating
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …

Ultrasmall rhodium nanozyme with RONS scavenging and photothermal activities for anti-inflammation and antitumor theranostics of colon diseases

Z Miao, S Jiang, M Ding, S Sun, Y Ma, MR Younis… - Nano Letters, 2020 - ACS Publications
Colitis-associated colorectal cancer (CAC), in which chronic inflammation is a well-
recognized carcinogen, requires concurrent anti-inflammation and antitumor treatments in …

Metal–Organic Framework Modified MoS2 Nanozyme for Synergetic Combating Drug‐Resistant Bacterial Infections via Photothermal Effect and Photodynamic …

ZY Liao, YM Xia, JM Zuo, T Wang… - Advanced …, 2022 - Wiley Online Library
Bacterial infections have become major threats to public health all over the world. With the
emergence of antibiotic resistance, it is urgent to develop novel antimicrobial materials to …

Dual nanozyme-driven PtSn bimetallic nanoclusters for metal-enhanced tumor photothermal and catalytic therapy

Y Zhu, R Zhao, L Feng, C Wang, S Dong, MV Zyuzin… - ACS …, 2023 - ACS Publications
Specific generation of reactive oxygen species (ROS) within tumors in situ catalyzed by
nanozymes is a promising strategy for cancer therapeutics. However, it remains a significant …

Polymetallic Hybrid Nanoplatform with Hyperthermia‐Amplified Dual Enzyme‐Like Activities for Efficient Speeded‐Up Bacterially Infected Wound Healing

X He, Z Deng, JT Hou, X Sun, D Jiang… - Advanced Materials …, 2022 - Wiley Online Library
Antibiotic‐independent artificial nanozymes exhibit excellent biocatalytic activity, and can
generate sufficient reactive oxygen species (ROS) for potential applications in the field of …