Advances in neurobiology of the neuromuscular junction: implications for the anesthesiologist

M Naguib, P Flood, JJ McArdle… - The Journal of the …, 2002 - pubs.asahq.org
THE mammalian neuromuscular junction (NMJ) is one of the most studied and best
understood synapses. Recent work has brought forth new information as to development …

Neuromuscular junction in health and disease

NP Hirsch - British journal of anaesthesia, 2007 - academic.oup.com
A number of illnesses and other factors can affect the function of the neuromuscular junction
(NMJ). These may have an affect at pre-or post-junctional sites. This review outlines the …

The neuromuscular junction: anatomical features and adaptations to various forms of increased, or decreased neuromuscular activity

MH Wilson, MR Deschenes - International journal of neuroscience, 2005 - Taylor & Francis
The neuromuscular junction (NMJ) allows communication between motor neurons and
muscle fibers. During development, marked morphological changes occur as the functional …

Interaction of muscle relaxants and local anesthetics at the neuromuscular junction

S Matsuo, DBS Rao, I Chaudry… - Anesthesia & Analgesia, 1978 - journals.lww.com
The effects on neuromuscular (NM) function of combinations of relaxants (d-tubocurarine,
pancuronium, and succinylcholine) and local anesthetics (cocaine, procaine, lidocaine …

The neuromuscular junction

AG Engel - Handbook of clinical neurology, 2008 - Elsevier
Publisher Summary The neuromuscular junction (NMJ) is a chemical synapse that is
anatomically and functionally differentiated for the transmission of a signal from the motor …

Monitoring of neuromuscular junction

D Padmaja, S Mantha - Indian Journal of Anaesthesia, 2002 - journals.lww.com
Neuromuscular blockers (NMBs) are widely used in anaesthesia practice. Simple
quantitative method to monitor their effects is desirable. Neuromuscular junction (NMJ) …

Safety factor at the neuromuscular junction

SJ Wood, CR Slater - Progress in neurobiology, 2001 - Elsevier
Reliable transmission of activity from nerve to muscle is necessary for the normal function of
the body. The term 'safety factor'refers to the ability of neuromuscular transmission to remain …

Development of the vertebrate neuromuscular junction

JR Sanes, JW Lichtman - Annual review of neuroscience, 1999 - annualreviews.org
▪ Abstract We describe the formation, maturation, elimination, maintenance, and
regeneration of vertebrate neuromuscular junctions (NMJs), the best studied of all synapses …

Structural factors influencing the efficacy of neuromuscular transmission

CR Slater - Annals of the New York Academy of Sciences, 2008 - Wiley Online Library
Neuromuscular junctions (NMJs) in different species share many features of structure and
function. At the same time, important differences distinguish, for example, human NMJs from …

The neuromuscular junction: muscle fibre type differences, plasticity and adaptability to increased and decreased activity

MR Deschenes, J Covault, WJ Kraemer, CM Maresh - Sports Medicine, 1994 - Springer
The neuromuscular junction (NMJ) of adult mammalian muscle is the site of the transduction
of electrical stimuli, generated by the nervous system, to the underlying muscle fibres …