HSPA2 is expressed in human tumors and correlates with clinical features in non-small cell lung carcinoma patients

D Scieglinska, A Gogler-Piglowska… - Anticancer …, 2014 - ar.iiarjournals.org
Background/Aim: It has been shown that HSPA2 protein, a testis-enriched member of
HSPA/HSP70 family, is important for cancer cell growth and metastasis. However, the status …

[HTML][HTML] Functional redundancy of HSPA1, HSPA2 and other HSPA proteins in non-small cell lung carcinoma (NSCLC); an implication for NSCLC treatment

DR Sojka, A Gogler-Pigłowska, N Vydra, AJ Cortez… - Scientific Reports, 2019 - nature.com
Heat shock proteins (HSPs) are a large group of chaperones considered critical for
maintaining cellular proteostasis. Their aberrant expression in tumors can modulate the …

Expression of HSPA2 in human hepatocellular carcinoma and its clinical significance

Y Fu, H Zhao, XS Li, HR Kang, JX Ma, FF Yao, N Du - Tumor Biology, 2014 - Springer
Hepatocellular carcinoma (HCC) remains one of the most common cancers worldwide.
HSPA2 has been highlighted as an important marker in many types of cancers. However …

[HTML][HTML] Overexpression of HSPA2 is correlated with poor prognosis in esophageal squamous cell carcinoma

H Zhang, W Chen, CJ Duan, CF Zhang - World journal of surgical oncology, 2013 - Springer
Background Heat shock-related 70 kDa protein 2 (HSPA2) has been identified as a potential
cancer-promoting protein expressed at abnormal levels in a subset of cancers. However, its …

[HTML][HTML] Expression and clinical significance of HSPA2 in pancreatic ductal adenocarcinoma

H Zhang, H Gao, C Liu, Y Kong, C Wang, H Zhang - Diagnostic pathology, 2015 - Springer
Background It has been shown that heat shock-related 70-kDa protein 2 (HSPA2), a
member of the HSP70 family of heat shock proteins, is important for cancer cell growth and …

The HspA2 protein localizes in nucleoli and centrosomes of heat shocked cancer cells

D Ścieglińska, W Pigłowski, A Mazurek… - Journal of cellular …, 2008 - Wiley Online Library
The human HSPA2 gene, which belongs to the HSP70 family of heat shock genes, is a
counterpart of rodent testis‐specific HspA2 gene. Rodent genes are expressed mainly in …

[HTML][HTML] HSPA2 chaperone contributes to the maintenance of epithelial phenotype of human bronchial epithelial cells but has non-essential role in supporting …

DR Sojka, A Gogler-Pigłowska, K Klarzyńska… - Cancers, 2020 - mdpi.com
Simple Summary Heat shock proteins A (HSPA) are molecular chaperones that play a
central role in the cellular protein quality control. One of them is HSPA2 which recently was …

[HTML][HTML] Upregulation of HSPA1A/HSPA1B/HSPA7 and downregulation of HSPA9 were related to poor survival in colon cancer

Y Guan, X Zhu, J Liang, M Wei, S Huang… - Frontiers in oncology, 2021 - frontiersin.org
The human HSP70 family is a type of heat shock protein (HSP), consisting of 13 members
encoded by the HSPA genes. HSPs play important roles in regulating cellular responses …

HSPA4 knockdown retarded progression and development of colorectal cancer

M Zhang, W Dai, Z Li, L Tang, J Chen… - Cancer Management …, 2021 - Taylor & Francis
Purpose Colorectal cancer (CRC) is a common malignancy associated with high morbidity
and mortality. Heat shock 70 kDa protein 4 (HSPA4) has been shown to exert regulatory …

HSPA6 and its role in cancers and other diseases

B Song, S Shen, S Fu, J Fu - Molecular Biology Reports, 2022 - Springer
Abstract Heat Shock Protein Family A (Hsp70) Member 6 (HSPA6)(Online Mendelian
Inheritance in Man: 140555) belongs to the HSP70 family and is a partially conserved …