Abstract Sperm associated antigen 9 (SPAG9) protein has been found to play an important
role in cancer progression but the involved mechanisms are still obscure. Its clinical …

Abstract Proteasome α5 subunit (PSMA5) is related to poor prognosis in various cancers.
The first therapeutic proteasome inhibitor, bortezomib, induces apoptosis, suppressing cell …

Objective Lung cancer (LC) is one of the most prevalent malignant tumors worldwide. As a
subtype of LC, lung squamous cell carcinoma (LUSC) has a 5-year survival rate of less than …

Abstract Sperm‐associated antigen 5 (SPAG5) is a mitotic spindle protein that regulates the
separation of sister chromatids into daughter cells. Recent studies have discovered its …

Summary SASH1 (SAM-and SH3-domain containing 1), a novel candidate tumor
suppressor, has attracted attention due to its role in intracellular signal transduction and its …

Hypoxia leads to the upregulation of a variety of genes mediated largely via the hypoxia
inducible transcription factor (HIF). Prominent HIF‐regulated target genes such as the …

Background Overexpression of sperm‐associated antigen 5 (SPAG5) is a marker of poor
prognosis in numerous tumors and is recognized as an index of tumor proliferation; …

Abstract Sphingosine kinase1 (SphK1) is an oncogenic enzyme that regulates tumor cell
apoptosis, proliferation and survival. SphK1 has been reported to promote the development …

Background It is important to explore novel molecules that play a key role in esophageal
cancer (ESCA) progression. Methods Two ESCA tissue expression profile microarrays …

Chromosomal and genome abnormalities of 3p are frequent in many epithelial tumors,
including lung cancer. Several critical regions with a high frequency of hemi-and …