A problem maxillofacial surgeons face is a lack of sufficient autogenous oral mucosa for
reconstruction of the oral cavity. Split-thickness or oral mucosa grafts require more than one …

In 2004, we reported a novel method of repairing a human mandible by in vivo tissue
engineering. The patient served as his own bioreactor as the exogenously prepared …

Tissue-engineered oral mucosal equivalents (OME) are being increasingly used to measure
toxicity, drug delivery, and to model oral diseases. Current OME mainly comprise normal …

The aim of this study was to determine the optimal stage of development at which transplant
human ex vivo-produced oral mucosa equivalents (EVPOMEs) in vivo. EVPOMEs were …

Advances in tissue engineering have permitted the three-dimensional (3D) reconstruction of
human oral mucosa for various in vivo and in vitro applications. Tissue-engineered oral …

Reconstruction of large oral mucosa defects is often challenging, since the shortage of
healthy oral mucosa to replace the excised tissues is very common. In this context, tissue …

PURPOSE: The objective of this study was to investigate the role of grafted oral
keratinocytes in a transplanted ex vivo–produced oral mucosa equivalent (EVPOME) in the …

Our goal was to investigate in vivo tissue formation following the grafting of engineered
human oral mucosa to demonstrate its usefulness in replacing mucosal defects in the oral …

Tissue Engineering is an emerging field of medical research in which there is tremendous
activity. Many of these products rely on the use of a cellular component co-formulated with a …

Saliva is an important compound produced by the salivary glands and performs numerous
functions. Hyposalivation (dry mouth syndrome) is a deleterious condition often resulting …