Segmental copy-number variations (CNVs) in the human genome are associated with
developmental disorders and susceptibility to diseases. More importantly, CNVs may …

Despite considerable excitement over the potential functional significance of copy-number
variants (CNVs), we still lack knowledge of the fine-scale architecture of the large majority of …

Genomic copy number variation (CNV) is a recently identified form of global genetic
variation in the human genome. The Affymetrix GeneChip 100 and 500 K SNP genotyping …

Copy number variation (CNV) of DNA sequences is functionally significant but has yet to be
fully ascertained. We have constructed a first-generation CNV map of the human genome …

DNA copy number variation has long been associated with specific chromosomal
rearrangements and genomic disorders, but its ubiquity in mammalian genomes was not …

A major contribution to the genome variability among individuals comes from deletions and
duplications—collectively termed copy number variations (CNVs)—which alter the diploid …

Copy-number variation (CNV) is the most prevalent type of structural variation in the human
genome, and contributes significantly to genetic heterogeneity. It has already been …

Inter-individual genomic variations have recently become evident with advances in
sequencing techniques and genome-wide array comparative genomic hybridization. Among …

Recent discovery of the copy number variation (CNV) in normal individuals has widened our
understanding of genomic variation. However, most of the reported CNVs have been …

A considerable and unanticipated plasticity of the human genome, manifested as inter-
individual copy number variation, has been discovered. These structural changes constitute …