While bone tissue is known for its inherent regenerative abilities, various pathological
conditions and trauma can disrupt its meticulously regulated processes of bone formation …

Embryogenic developmental processes involve a tightly controlled regulation between
mechanical forces and biochemical cues such as growth factors, matrix proteins, and …

Despite its intrinsic ability to regenerate form and function after injury, bone tissue can be
challenged by a multitude of pathological conditions. While innovative approaches have …

Over the past few years, attention has been focused on the therapeutic roles in designing
bone scaffolds for successful repair and regeneration. Indeed, biologically dynamic events …

Large-sized bone defects are a great challenge in clinics and considerably impair the quality
of patients' daily life. Tissue engineering strategies using cells, scaffolds, and bioactive …

Disrupted bone metabolism can lead to delayed fracture healing or non-union, often
requiring intervention to correct. Although the current clinical gold standard bone graft …

Bone is a hard yet dynamic tissue with remarkable healing capacities. Research to date has
greatly advanced the understanding of how bone heals and has led to marked success in …

Inspired by the physiological events of the “wound healing cascade”, the integration of
biomaterials and growth factors is generally accepted as an emerging and powerful strategy …

Zinc (Zn) is one of the most important trace elements in the human body and plays a key role
in various physiological processes, especially in bone metabolism. Zn-containing materials …

In recent years, bone regeneration has emerged as a remarkable field that offers promising
guidance for treating bone-related diseases, such as bone defects, bone infections, and …