Background: Nowadays, ionizing radiation is used for several applications in medicine,
industry, agriculture, and nuclear power generation. Besides the beneficial roles of ionizing …

Over the last decade, evidence has emerged to support a role for the antidiabetic drug
metformin in the prevention and treatment of cancer. In particular, recent studies …

Introduction: Metformin, the most widely used treatment for diabetes, is lethal to cancer cells
and increases in toxicity when used in combination with radiation. In addition to various …

Metformin, a biguanide drug used in the treatment of type II diabetes, was evaluated alone
and in combination with amifostine, captopril, MESNA or N-acetyl-cysteine (NAC) for its …

The anti-cancer effects of metformin, the most widely used drug for type 2 diabetes, alone or
in combination with ionizing radiation were studied with MCF-7 human breast cancer cells …

Several molecules are being investigated for their ability to enhance the anti-tumor effect of
radiotherapy. The widely prescribed antidiabetic drug metformin has been suggested to …

Background and purpose Metformin is commonly prescribed to treat type 2 diabetes, and
has additional potential as a cancer prophylactic and therapeutic. Metformin activates AMPK …

Metformin is a first-line used agent for type II diabetes with few side effects. The
antineoplastic effect of metformin was widely explored recently. Metformin may also be a …

Recent evidences have demonstrated the potential of metformin as a novel agent for cancer
prevention and treatment. Here, we investigated its ability of radiosensitization and the …

Metformin is a widely prescribed drug used in the treatment of patients with type 2 diabetes.
In this study, the radioprotective effect of metformin was investigated against cytotoxicity and …