Ginsenoside Rg1 Delays Chronological Aging in a Yeast Model via CDC19-and SDH2-Mediated Cellular Metabolism
S Wang, J Qiao, C Jiang, D Pan, S Yu, J Chen, S Liu… - Antioxidants, 2023 - mdpi.com
Ginsenosides, active substances in Panax ginseng CA Meyer (ginseng), extend lifespan in
multiple species, ameliorate age-associated damage, and limit functional decline in multiple …
multiple species, ameliorate age-associated damage, and limit functional decline in multiple …
Ginsenoside Rb1 retards aging process by regulating cell cycle, apoptotic pathway and metabolism of aging mice
S Yu, H Xia, Y Guo, X Qian, X Zou, H Yang… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Ginsenoside Rb1 (GRb1), an active ingredient of
traditional Chinese medicine Panax ginseng CA Meyer, has displayed various activities …
traditional Chinese medicine Panax ginseng CA Meyer, has displayed various activities …
[HTML][HTML] Stereoisomer-specific ginsenoside 20 (S)-Rg3 reverses replicative senescence of human diploid fibroblasts via Akt-mTOR-Sirtuin signaling
KE Yang, HJ Jang, IH Hwang, EM Hong… - Journal of ginseng …, 2020 - Elsevier
Background The replicative senescence of human dermal fibroblasts (HDFs) is
accompanied by growth arrest. In our previous study, the treatment of senescent HDFs with …
accompanied by growth arrest. In our previous study, the treatment of senescent HDFs with …
Ginsenoside extract from ginseng extends lifespan and health span in Caenorhabditis elegans
H Wang, S Zhang, L Zhai, L Sun, D Zhao, Z Wang… - Food & Function, 2021 - pubs.rsc.org
Nutrition intervention has become a potential strategy to improve healthspan and prolong
lifespan. Ginseng has been used for thousands of years and developed as a functional food …
lifespan. Ginseng has been used for thousands of years and developed as a functional food …
Ginsenoside Prolongs the Lifespan of C. elegans via Lipid Metabolism and Activating the Stress Response Signaling Pathway
X Yu, H Li, D Lin, W Guo, Z Xu, L Wang… - International journal of …, 2021 - mdpi.com
Panax ginseng is a valuable traditional Chinese medicine in Northeast China. Ginsenoside,
the active component of ginseng, has not been investigated much for its effects on aging and …
the active component of ginseng, has not been investigated much for its effects on aging and …
[HTML][HTML] Proteomic analyses reveal that ginsenoside Rg3 (S) partially reverses cellular senescence in human dermal fibroblasts by inducing peroxiredoxin
IS Jang, E Jo, SJ Park, SJ Baek, IH Hwang… - Journal of Ginseng …, 2020 - Elsevier
Background The cellular senescence of primary cultured cells is an irreversible process
characterized by growth arrest. Restoration of senescence by ginsenosides has not been …
characterized by growth arrest. Restoration of senescence by ginsenosides has not been …
Black ginseng ameliorates cellular senescence via p53-p21/p16 pathway in aged mice
Simple Summary The goal of this study was to examine if BG impacts the aging process,
specifically cellular senescence, using in vitro and aged mouse models. Primary mouse …
specifically cellular senescence, using in vitro and aged mouse models. Primary mouse …
Red Ginseng Attenuates the Hepatic Cellular Senescence in Aged Mice
Simple Summary The aim of this study was to explore the potential impact of red ginseng
(RG) on age-associated cellular senescence through in vitro, ex vivo, and 19-month-old …
(RG) on age-associated cellular senescence through in vitro, ex vivo, and 19-month-old …
The anti-aging mechanism of ginsenosides with medicine and food homology
T Tian, CN Ko, W Luo, D Li, C Yang - Food & Function, 2023 - pubs.rsc.org
With the acceleration of global aging and the rise in living standards, the achievement of
healthy aging is becoming an imperative issue globally. Ginseng, a medicinal plant that has …
healthy aging is becoming an imperative issue globally. Ginseng, a medicinal plant that has …
Ginsenoside Rg1 protects against d-galactose induced fatty liver disease in a mouse model via FOXO1 transcriptional factor
R Qi, R Jiang, H Xiao, Z Wang, S He, L Wang, Y Wang - Life Sciences, 2020 - Elsevier
Aims Rg1 is the most active component of traditional Chinese medicine ginseng, having anti-
aging and anti-oxidative stress features in multiple organs. Cellular senescence of …
aging and anti-oxidative stress features in multiple organs. Cellular senescence of …