More than 40 promising agents and agent combinations are being evaluated clinically as
chemopreventive drugs for major cancer targets. A few have been in vanguard, large‐scale …

Clinical chemoprevention trials of more than 30 agents and agent combinations are now in
progress or being planned. The most advanced agents are well known and are in large …

Chemoprevention drug development has the goal of identifying safe and effective
chemopreventive agents for clinical use. Several distinctive strategies are pursued in …

The seminal epidemiological observation that nonsteroidal anti-inflammatory drugs
(NSAIDs) prevent colon and possibly other cancers has spurred novel approaches to cancer …

During recent years, multidisciplinary studies in epidemiology and molecular biology, as
well as preclinical studies, have contributed much to our understanding of the etiology of …

The limited success of current treatments for most advanced common malignancies
highlights the importance of cancer prevention. Clinical trials on cyclooxygenase (COX) …

This two-part series provides an up-to-date summary of the various chemopreventive agents
currently in development and testing. Part 1, published in last month's issue, focused on the …

Chemoprevention represents a highly promising approach for the control of cancer. That
nonsteroidal anti-inflammatory drugs (NSAIDs) prevent colon and other cancers has led to …

Cancer chemoprevention is a new approach in the management of cancer. Traditional
cytotoxic chemotherapeutic approaches cannot cure most advanced solid malignancies …

Large bowel cancer is not only the third most frequent cancer in the world but is one of the
most common human malignancies in Western countries, including North America. In recent …