Osteoarthritis (OA) is the most common form of joint disease. Histopathologically, OA is
characterized by a progressive loss of articular cartilage, osteophyte formation, thickening of …

Osteoarthritis (OA), the most common form of degenerative joint disease, is linked to high
morbidity. It is predicted to be the single greatest cause of disability in the general population …

Osteoarthritis (OA) is the most common form of joint disease in middle‐aged and older
individuals. Previous studies have shown that over‐expression of matrix‐degrading …

Transcription factors play important roles in the regulation of cartilage development by
controlling the expression of chondrogenic genes. Genetic studies have revealed that …

The development of disease‐modifying pharmacologic therapy for osteoarthritis (OA)
currently faces major obstacles largely because the regulatory mechanisms for the function …

Osteoarthritis (OA) is a joint disease that involves degeneration of articular cartilage, limited
intraarticular inflammation manifested by synovitis and changes in the subchondral bone …

Objectives Adult mice lacking the transcription factor NFAT1 exhibit osteoarthritis (OA). The
precise molecular mechanism for NFAT1 deficiency-induced osteoarthritic cartilage …

Osteoarthritis (OA) was once viewed originally as a mechanical disease of “wear and tear,”
but advances made during the past two decades suggest that abnormal biomechanics …

Osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage
degradation but also synovial membrane inflammation, osteophyte formation and …

The aim of this review is to provide an updated review of the epigenetic factors involved in
the onset and development of osteoarthritis (OA). OA is a prevalent degenerative joint …