Osteoarthritis: novel molecular mechanisms increase our understanding of the disease pathology
Although osteoarthritis (OA) is the most common musculoskeletal condition that causes
significant health and social problems worldwide, its exact etiology is still unclear. With an …
significant health and social problems worldwide, its exact etiology is still unclear. With an …
NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation
The origin and differentiation mechanism of articular chondrocytes remain poorly
understood. Broadly, the difference in developmental mechanisms of articular and growth …
understood. Broadly, the difference in developmental mechanisms of articular and growth …
Osteoarthritis: a narrative review of molecular approaches to disease management
Osteoarthritis (OA) is a chronic, progressive degenerative whole joint disease that affects the
articular cartilage, subchondral bone, ligaments, capsule, and synovium. While it is still …
articular cartilage, subchondral bone, ligaments, capsule, and synovium. While it is still …
Cartilage biology, pathology, and repair
D Umlauf, S Frank, T Pap, J Bertrand - Cellular and molecular life sciences, 2010 - Springer
Osteoarthritis is one of the most common forms of musculoskeletal disease and the most
prominent type of arthritis encountered in all countries. Although great efforts have been …
prominent type of arthritis encountered in all countries. Although great efforts have been …
Pathobiology of osteoarthritis: pathomechanisms and potential therapeutic targets
HI Roach, T Aigner, S Soder, J Haag… - Current Drug …, 2007 - ingentaconnect.com
Osteoarthritis, a degenerative joint disease, is the most disabling condition of the Western
world. It affects first and foremost the articular cartilages and leads to a molecular and …
world. It affects first and foremost the articular cartilages and leads to a molecular and …
[HTML][HTML] Current concepts in the pathogenesis of osteoarthritis
S Krasnokutsky, M Attur, G Palmer, J Samuels… - Osteoarthritis and …, 2008 - Elsevier
Osteoarthritis (OA) is a degenerative joint disease that progressively causes loss of joint
function and is the leading source of physical disability and impaired quality of life in …
function and is the leading source of physical disability and impaired quality of life in …
Microenvironment in subchondral bone: predominant regulator for the treatment of osteoarthritis
W Hu, Y Chen, C Dou, S Dong - Annals of the Rheumatic Diseases, 2021 - ard.bmj.com
Osteoarthritis (OA) is a degenerative joint disease in the elderly. Although OA has been
considered as primarily a disease of the articular cartilage, the participation of subchondral …
considered as primarily a disease of the articular cartilage, the participation of subchondral …
Mechanism of cartilage destruction in osteoarthritis.
N Ishiguro, T Kojima, AR Poole - Nagoya journal of medical science, 2002 - europepmc.org
Osteoarthritis (OA) is one of the most common diseases among the elderly. For many years,
OA was considered a normal result of the aging process with few treatment options …
OA was considered a normal result of the aging process with few treatment options …
Regulatory mechanisms of chondrogenesis and implications for understanding articular cartilage homeostasis
C Hidaka, MB Goldring - Current Rheumatology Reviews, 2008 - ingentaconnect.com
Studies of chondrogenesis and embryonic limb development offer a wealth of knowledge
regarding signals that regulate the behavior of chondrocytes. Many such chondrogenic …
regarding signals that regulate the behavior of chondrocytes. Many such chondrogenic …
[HTML][HTML] Osteoarthritis year in review 2013: biology
RF Loeser - Osteoarthritis and Cartilage, 2013 - Elsevier
The purpose of this review was to present highlights from the published literature on the
topic of the biology of osteoarthritis (OA). A PubMed search was conducted in order to locate …
topic of the biology of osteoarthritis (OA). A PubMed search was conducted in order to locate …