The purpose of this study was to assess the expression of cell adhesion molecules ICAM-1
(intercellular adhesion molecule-1) and VCAM-1 (vascular cell adhesion molecule-1) in …

The effect of macrophages on rabbit vascular smooth muscle phenotype and proliferative
ability was examined using ultrastructural morphometry. The volume fraction of myofilaments …

A wide variety of cell populations, including both immune and endothelial cells, participate in
the pathogenesis of atherosclerosis. Among these groups, macrophages deserve special …

Atherosclerosis is a chronic disease characterized by the deposition of excessive
cholesterol in the arterial intima. Macrophage foam cells play a critical role in the occurrence …

It is now clear that hypercholesterolemia can, in some instances, be a necessary and
sufficient cause of premature atherosclerosis. This has been best established in patients …

Sections of human atherosclerotic lesions of different stages show that, in early lesions, the
acellular lipid core is usually immediately adjacent to the deepest edge of a collection of …

Foam cells, either myogenic or macrophagic, are commonly detected in experimental and
human fibro-atheromatous plaques. Their role in human atherosclerosis is not yet …

Because of a close association between platelets and macrophages in early fatty streak
lesions, the hypothesis was tested that platelets contribute to lesion progression by directly …

Atherosclerosis is a chronic immune-inflammatory disease in which the interactions of
monocytes with activated endothelium are crucial events leading to atherosclerotic alteration …