Revitalizing Cancer Treatment: Exploring the Role of Drug Repurposing

RR Malla, S Viswanathan, S Makena, S Kapoor… - Cancers, 2024 - mdpi.com
Simple Summary Drug repurposing is emerging as a promising avenue for addressing
clinical challenges in treating drug-resistant and metastatic cancers. As a case study, some …

Drug repurposing for cancer.

J Banerjee, AK Tiwari, S Banerjee - Progress in Molecular Biology …, 2024 - europepmc.org
In the dynamic landscape of cancer therapeutics, the innovative strategy of drug repurposing
emerges as a transformative paradigm, heralding a new era in the fight against …

Overcoming cancer therapeutic bottleneck by drug repurposing

Z Zhang, L Zhou, N Xie, EC Nice, T Zhang… - Signal transduction and …, 2020 - nature.com
Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …

Drug repurposing for cancer therapy

Y Xia, M Sun, H Huang, WL Jin - Signal Transduction and Targeted …, 2024 - nature.com
Cancer, a complex and multifactorial disease, presents a significant challenge to global
health. Despite significant advances in surgical, radiotherapeutic and immunological …

Drug Repurposing: Exploring Potential Anti-Cancer Strategies by Targeting Cancer Signalling Pathways

N Haddad, SM Gamaethige, N Wehida, A Elbediwy - Biology, 2024 - mdpi.com
Simple Summary The repurposing of drugs is an important and rapidly growing field in the
treatment of cancer. The main advantage of drug repurposing is using currently established …

Unlocking hidden potential: advancements, approaches, and obstacles in repurposing drugs for cancer therapy

FR Weth, GB Hoggarth, AF Weth, E Paterson… - British Journal of …, 2024 - nature.com
High rates of failure, exorbitant costs, and the sluggish pace of new drug discovery and
development have led to a growing interest in repurposing “old” drugs to treat both common …

Repurposing drugs in oncology: next steps

C Verbaanderd, L Meheus, I Huys, P Pantziarka - Trends in cancer, 2017 - cell.com
The repurposing of existing non-cancer drugs is a potential source of new treatment options
for cancer patients with high unmet medical needs. While scientific research is progressing …

Repurposed Drugs Targeting Cancer Signaling Pathways: Dissecting New Mechanism of Action Through In Vitro and In Vivo Analyses

E López-Urrutia, T Padilla-Benavides… - Frontiers in …, 2021 - frontiersin.org
In today's fast-paced society, efficiency is critical in many aspects, especially in costly,
resourceintensive processes such as drug discovery and development. Technological …

Drug repurposing—an emerging strategy in cancer therapeutics

KS Turabi, A Deshmukh, S Paul, D Swami… - Naunyn-Schmiedeberg's …, 2022 - Springer
Cancer is a complex disease affecting millions of people around the world. Despite
advances in surgical and radiation therapy, chemotherapy continues to be an important …

Adopting drug repurposing to overcome drug resistance in cancer

E Shankar, V Subramaniam… - Frontiers in Cell and …, 2023 - frontiersin.org
Despite significant technological advances the etiology of cancer and mechanism disease
progression, and their translation into therapeutic benefits has been considerably slow …