Melatonin regulates lipid metabolism in porcine cumulus–oocyte complexes via the melatonin receptor 2

JX Jin, JT Sun, CQ Jiang, HD Cui, Y Bian, S Lee… - Antioxidants, 2022 - mdpi.com
Previous studies suggest that the inclusion of melatonin (MTn) in in vitro maturation
protocols improves the developmental competence of oocytes by scavenging reactive …

Melatonin modulates lipid metabolism in porcine cumulus–oocyte complex via its receptors

T Zhu, S Guan, D Lv, M Zhao, L Yan, L Shi… - Frontiers in cell and …, 2021 - frontiersin.org
Lipid is a crucial energy resource for mammalian oocyte. Melatonin could benefit the
maturation of porcine oocyte in vitro, but the related mechanism is not elucidated yet. In the …

Melatonin regulates lipid metabolism in porcine oocytes

JX Jin, S Lee, A Taweechaipaisankul… - Journal of pineal …, 2017 - Wiley Online Library
It is being increasingly recognized that the processes of lipogenesis and lipolysis are
important for providing an essential energy source during oocyte maturation and embryo …

Melatonin‐induced increase of lipid droplets accumulation and in vitro maturation in porcine oocytes is mediated by mitochondrial quiescence

B He, C Yin, Y Gong, J Liu, H Guo… - Journal of cellular …, 2018 - Wiley Online Library
Melatonin, the major pineal secretory product, has a significant impact on the female
reproductive system. Recently, the beneficial effects of melatonin on mammalian oocyte …

Melatonin improves the fertilization capacity and developmental ability of bovine oocytes by regulating cytoplasmic maturation events

XM Zhao, N Wang, HS Hao, CY Li… - Journal of pineal …, 2018 - Wiley Online Library
Melatonin is a well‐characterized antioxidant that has been successfully used to protect
oocytes from reactive oxygen species during in vitro maturation (IVM), resulting in improved …

Evidence of melatonin synthesis in the cumulus oocyte complexes and its role in enhancing oocyte maturation in vitro in cattle

M El‐Raey, M Geshi, T Somfai… - Molecular …, 2011 - Wiley Online Library
Melatonin is a multifunctional molecule that mediates several circadian and seasonal
reproductive processes. The exact role of melatonin in modulating reproduction, however, is …

Melatonin supplementation during prolonged in vitro maturation improves the quality and development of poor‐quality porcine oocytes via anti‐oxidative and anti …

T Lin, JE Lee, JW Kang, RK Oqani… - Molecular …, 2018 - Wiley Online Library
Poor‐quality oocytes (those with 1–2 layers of cumulus cells) typically possess low meiotic
competence and development. Prolonging the duration of in vitro maturation (IVM; 52 hr) …

Effects of melatonin on in vitro maturation of porcine oocyte and expression of melatonin receptor RNA in cumulus and granulosa cells

JT Kang, OJ Koo, DK Kwon, HJ Park… - Journal of pineal …, 2009 - Wiley Online Library
Melatonin is a multifunctional molecule that mediates several circadian and seasonal
processes in animal reproduction. Melatonin and its metabolites are antioxidants and free …

Melatonin rescues the development and quality of oocytes and cumulus cells after prolonged ovary preservation: An ovine in vitro model

I Sánchez-Ajofrín, A Martín-Maestro… - Theriogenology, 2022 - Elsevier
The preservation of ovaries beyond 7 h dramatically decreases the developmental potential
of oocytes to reach the blastocyst stage during in vitro embryo production. Here we …

[HTML][HTML] Melatonin improves the quality of maternally aged oocytes by maintaining intercellular communication and antioxidant metabolite supply

H Zhang, C Li, D Wen, R Li, S Lu, R Xu, Y Tang, Y Sun… - Redox Biology, 2022 - Elsevier
In mammalian ovaries, oocytes are physically coupled to somatic granulosa cells, and this
coupling is crucial for the growth and development of competent oocytes as it mediates the …