Diverse expression patterns of the EMT suppressor grainyhead‐like 2 (GRHL 2) in normal and tumour tissues
S Riethdorf, S Frey, S Santjer… - … Journal of Cancer, 2016 - Wiley Online Library
The transcription factor grainyhead‐like 2 (GRHL2) plays a crucial role in various
developmental processes. Although GRHL2 recently has attracted considerable interest in …
developmental processes. Although GRHL2 recently has attracted considerable interest in …
Silencing of GRHL2 induces epithelial‑to‑mesenchymal transition in lung cancer cell lines with different effects on proliferation and clonogenic growth
N Kawabe, K Matsuoka, K Komeda… - Oncology …, 2023 - spandidos-publications.com
Abstract Grainyhead‑like 2 (GRHL2) is a transcription factor that suppresses epithelial‑to‑
mesenchymal transition (EMT). It has been previously shown that GRHL2 can confer both …
mesenchymal transition (EMT). It has been previously shown that GRHL2 can confer both …
Suppression of the epithelial–mesenchymal transition by Grainyhead-like-2
B Cieply, P Riley IV, PM Pifer, J Widmeyer, JB Addison… - Cancer research, 2012 - AACR
Grainyhead genes are involved in wound healing and developmental neural tube closure. In
light of the high degree of similarity between the epithelial–mesenchymal transitions (EMT) …
light of the high degree of similarity between the epithelial–mesenchymal transitions (EMT) …
[HTML][HTML] Expression of transcription factor grainyhead-like 2 is diminished in cervical cancer
LA Torres-Reyes, L Alvarado-Ruiz… - … Journal of Clinical …, 2014 - ncbi.nlm.nih.gov
The transcription factor grainyhead-like 2 (GRHL2) is evolutionarily conserved in many
different species, and is involved in morphogenesis, epithelial differentiation, and the control …
different species, and is involved in morphogenesis, epithelial differentiation, and the control …
[HTML][HTML] Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer
Using a retrovirus-mediated cDNA expression cloning approach, we identified the
grainyhead-like 2 (GRHL2) transcription factor as novel protooncogene. Overexpression of …
grainyhead-like 2 (GRHL2) transcription factor as novel protooncogene. Overexpression of …
[HTML][HTML] Grhl2 determines the epithelial phenotype of breast cancers and promotes tumor progression
Until now the essential transcription factor that determines the epithelial phenotype of breast
cancer has not been identified and its role in epithelial-to-mesenchymal transition (EMT) and …
cancer has not been identified and its role in epithelial-to-mesenchymal transition (EMT) and …
Grainyhead-like protein 2: the emerging role in hormone-dependent cancers and epigenetics
RM Reese, MM Harrison, ET Alarid - Endocrinology, 2019 - academic.oup.com
In mammals, the grainyhead-like transcription factor (GRHL) family is composed of three
nuclear proteins that are responsible for driving epithelial cell fate: GRHL1, GRHL2, and …
nuclear proteins that are responsible for driving epithelial cell fate: GRHL1, GRHL2, and …
[HTML][HTML] Suppressor gene GRHL1 is associated with prognosis in patients with oesophageal squamous cell carcinoma
M Li, Z Li, X Guan, Y Qin - Oncology Letters, 2019 - spandidos-publications.com
Grainyhead like transcription factor 1 (GRHL1) is among the key family genes encoding
transcription factors that serve important roles in inhibiting tumor cell clone growth …
transcription factors that serve important roles in inhibiting tumor cell clone growth …
Roles of Grainyhead-like transcription factors in cancer
SM Frisch, JC Farris, PM Pifer - Oncogene, 2017 - nature.com
The mammalian homologs of the D. melanogaster Grainyhead gene, Grainyhead-like 1–3
(GRHL1, GRHL2 and GRHL3), are transcription factors implicated in wound healing …
(GRHL1, GRHL2 and GRHL3), are transcription factors implicated in wound healing …
[HTML][HTML] Grainyhead-like 2 as a double-edged sword in development and cancer
J He, C Feng, H Zhu, S Wu, P Jin… - American journal of …, 2020 - ncbi.nlm.nih.gov
Abstract Grainyhead-like 2 (GRHL2), one of the three homologs of Drosophila grainyhead,
contributes to epithelial morphogenesis and differentiation. Dysregulation of GRHL2 has …
contributes to epithelial morphogenesis and differentiation. Dysregulation of GRHL2 has …