A method is reported for the simultaneous determination of ceftazidime and avibactam in
human plasma and cerebrospinal fluid utilizing high-performance liquid chromatography …

Ceftazidime is an antibiotic belonging to the third generation of the cephalosporin family. It is
indicated in the treatment of serious, simple or mixed bacterial infections, and its …

Background: Combination therapies have gained momentum in the disease management
strategies of various indications. While it is challenging and more time consuming to develop …

A rapid, accurate, and sensitive high-performance liquid chromatographic (HPLC) method
was developed and validated for the determination of ceftazidime in pharmaceuticals. The …

Abstract What is Known and Objective Carbapenem‐resistant Gram‐negative bacterial
pathogens continue to threaten public health. Avibactam (AVI), a novel non‐β‐lactam β …

A high-performance liquid chromatography procedure was developed to analyze
ceftazidime concentrations in plasma. The procedure consisted of solid phase extraction …

Therapeutic drug monitoring of β-lactam antibiotics is increasingly used for dose
optimization in the individual patient to increase efficacy and reduce the risk of toxicity. The …

Objectives To describe the pharmacokinetics/pharmacodynamics (PK/PD) of
ceftazidime/avibactam in critically ill patients with CNS infections. Methods A prospective …

Publisher Summary This chapter discusses the analytical profile of ceftazidime. Ceftazidime
pentahydrate 1.16 g is approximately equivalent to 1 g of anhydrous ceftazidime. The …

Ceftazidime is an established third-generation cephalosporin antibiotic frequently
administered to intensive care patients. To overcome drug resistance of pathogens, it is …