Surfactant proteins (SP)-A and-D are members of the collectin family of host defense
proteins that share four distinct structural domains: NH2-terminal oligomerization …

Surfactant protein D (SP-D) is a member of the collectin family of innate defense proteins.
Members of this family share four distinct structural domains: an N-terminal cross-linking …

The N-terminal domains of the lung collectins, surfactant proteins A (SP-A) and D (SP-D),
are critical for surfactant phospholipid interactions and surfactant homeostasis, respectively …

Surfactant protein (SP)-A is a member of the collectin family of proteins and plays a role in
innate host defense of the lung. SP-A binds to the carbohydrates of lung pathogens via its …

Alveolar surfactant is a complex mixture of lipids and proteins that executes two disparate
functions. First, surfactant reduces surface tension at the air–liquid interface of the lung …

The constant challenge to the lung of inhaled microbes and noxious substances is largely
kept in check by the innate and adaptive immune systems. Whereas the adaptive immune …

Surfactant protein D (SP-D) is a member of the collectin family of the innate host defense
proteins. In the lung, SP-D is expressed primarily by type II cells. Gene-targeted SP-D …

Surfactant proteins A and D (SP-A and SP-D) are members of the collectin family of
polypeptides expressed in the respiratory tract that bind bacterial, fungal and viral …

Surfactant proteins-A and-D (SP-A and SP-D) are members of the collectin protein family.
Mice singly deficient in SP-A and SP-D have distinct phenotypes. Both have altered …

Both surfactant protein (SP) D and granulocyte-macrophage colony-stimulating factor (GM-
CSF) influence pulmonary surfactant homeostasis, with the deficiency of either protein …