Nanoparticle size-specific actin rearrangement and barrier dysfunction of endothelial cells
Y Liu, N Rogel, K Harada, L Jarett, CH Maiorana… - …, 2017 - Taylor & Francis
In this work, we evaluated the impact of gold nanoparticles on endothelial cell behavior and
function beyond the influence on cell viability. Five types of gold nanoparticles were studied …
function beyond the influence on cell viability. Five types of gold nanoparticles were studied …
Influence of shear stress and size on viability of endothelial cells exposed to gold nanoparticles
C Fede, G Albertin, L Petrelli, R De Caro… - Journal of Nanoparticle …, 2017 - Springer
Screening nanoparticle toxicity directly on cell culture can be a fast and cheap technique.
Nevertheless, to obtain results in accordance with those observed in live animals, the …
Nevertheless, to obtain results in accordance with those observed in live animals, the …
Gold nanoparticles disrupt actin organization and pulmonary endothelial barriers
This study explored the impact of gold nanoparticles on the metabolic activity and
morphology of human pulmonary endothelial cell monolayers. We developed a gold …
morphology of human pulmonary endothelial cell monolayers. We developed a gold …
Low-dose albumin-coated gold nanorods induce intercellular gaps on vascular endothelium by causing the contraction of cytoskeletal actin
Z Li, J Liu, K Ballard, C Liang, C Wang - Journal of Colloid and Interface …, 2023 - Elsevier
Cytotoxicity of nanoparticles, typically evaluated by biochemical-based assays, often
overlook the cellular biophysical properties such as cell morphology and cytoskeletal actin …
overlook the cellular biophysical properties such as cell morphology and cytoskeletal actin …
Evaluation of gold nanoparticles toxicity towards human endothelial cells under static and flow conditions
C Fede, I Fortunati, V Weber, N Rossetto, F Bertasi… - Microvascular …, 2015 - Elsevier
A new in vitro model system, adding advection and shear stress associated with a flowing
medium, is proposed for the investigation of nanoparticles uptake and toxicity towards …
medium, is proposed for the investigation of nanoparticles uptake and toxicity towards …
Gold nanoparticles increase endothelial paracellular permeability by altering components of endothelial tight junctions, and increase blood-brain barrier permeability …
CH Li, MK Shyu, C Jhan, YW Cheng… - Toxicological …, 2015 - academic.oup.com
Abstract Gold nanoparticles (Au-NPs) are being increasingly used as constituents in
cosmetics, biosensors, bioimaging, photothermal therapy, and targeted drug delivery. This …
cosmetics, biosensors, bioimaging, photothermal therapy, and targeted drug delivery. This …
Endothelial barrier dysfunction induced by nanoparticle exposure through actin remodeling via caveolae/raft-regulated calcium signalling
The rapid development of modern nanotechnology has resulted in nanomaterial being use
in nearly all applications of life, raising the potential risk of nanomaterial exposure alongside …
in nearly all applications of life, raising the potential risk of nanomaterial exposure alongside …
Polyvinylpyrrolidone-coated gold nanoparticles inhibit endothelial cell viability, proliferation, and ERK1/2 phosphorylation and reduce the magnitude of endothelial …
T Mohamed, S Matou-Nasri, A Farooq… - International journal …, 2017 - Taylor & Francis
Background Gold nanoparticles (AuNPs) demonstrate clinical potential for drug delivery and
imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface …
imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface …
Gold nanoparticles compromise TNF-α-induced endothelial cell adhesion molecule expression through NF-κB and protein degradation pathways and reduce …
The aim of this study was to investigate the anti-inflammatory effects and mechanism of
action of the gold nanoparticles (AuNPs) on vascular injury. In vitro vascular endothelial cell …
action of the gold nanoparticles (AuNPs) on vascular injury. In vitro vascular endothelial cell …
Gold nanoparticle interactions with endothelial cells cultured under physiological conditions
C Freese, L Anspach, RC Deller, SJ Richards… - Biomaterials …, 2017 - pubs.rsc.org
PEGylated gold nanoparticles (AuNPs) have an extended circulation time after intravenous
injection in vivo and exhibit favorable properties for biosensing, diagnostic imaging, and …
injection in vivo and exhibit favorable properties for biosensing, diagnostic imaging, and …
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- endothelial cells actin rearrangement
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