Sepsis, defined as life-threatening organ dysfunction caused by a dysregulated host
response to an infection, remains a major challenge for clinicians and trialists. Despite …

Our understanding of sepsis and its resultant outcomes remains a paradox. On the one
hand, we know more about the pathophysiology of sepsis than ever before. However, this …

Introduction: Sepsis is characterized by a dysregulated host response to infection. Sepsis-
associated morbidity/mortality demands concerted research efforts toward therapeutic …

Sepsis, a dysregulated host response to infection characterized by organ failure, is one of
the leading causes of death worldwide. Disbalances of the immune response play an …

Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated
host response to infection. In sepsis, the immune response that is initiated by an invading …

Sepsis is life-threatening organ dysfunction due to dysregulated response to infection.
Patients with sepsis exhibit wide heterogeneity stemming from genetic, molecular, and …

Sepsis is a heterogeneous disease with variable clinical course and several clinical
phenotypes. As it is associated with an increased risk of death, patients with this condition …

Sepsis represents the host's systemic inflammatory response to a severe infection. It causes
substantial human morbidity resulting in hundreds of thousands of deaths each year …

Sepsis is defined as “a life‐threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection.” At present, sepsis continues to …

Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …