Background Despite animal evidence suggests that zinc modulates cadmium nephrotoxicity,
limited human data are available. Objective To test the hypothesis that low serum zinc …

Studies in vivo and in vitro have shown a protective effect of zinc against renal dysfunction
caused by cadmium exposure. However, limited human data is available. In this study, we …

Background Exposure to cadmium has been associated with nephropathy and implicated in
the development of diabetes and hypertension. The role of environmental metal exposure …

Background Environmental factors have been associated with the outbreak of chronic
kidney disease (CKD). We evaluated the association of Cadmium (Cd) exposure with the …

Background and objectives Exposure to cadmium (Cd) has been associated with aberrant
zinc and copper homeostasis. This study investigated if Cd exposure impairs renal …

High-level cadmium (Cd) exposure has long been known to induce nephropathy, severe
osteoporosis, and fractures in humans. More recent epidemiology, however, reveals that, in …

Background Several observational studies investigated the relationship between
environmental cadmium exposure and risk of chronic kidney disease (CKD). However …

Low-level cadmium exposure has adverse effects on chronic kidney disease (CKD);
however, the risk factors for elevated blood cadmium levels (BCLs) have not been studied in …

We conducted a study among residents of a small community contaminated with heavy
metals from a defunct zinc smelter and residents from a comparison community to determine …

Environmental cadmium and lead exposures are widespread, and both metals are
nephrotoxic at high exposure levels. Few studies have evaluated the associations between …