The mesolimbic dopamine (DA) system is known to play a role in cue-mediated reward-
seeking for natural rewards and drugs of abuse. Specifically, cholinergic and glutamatergic …

Cue exposure therapy (CET) reduces craving induced by drug-associated cues in
individuals with substance use disorders. A preclinical model of CET, cue extinction …

Many studies support a perspective that addictive drugs usurp brain circuits used by natural
rewards, especially for the dopamine-dependent reinforcing qualities of both drugs and …

A preclinical model of cue exposure therapy, cue extinction, reduces cue-induced cocaine
seeking that is goal-directed but not habit-like. Goal-directed and habitual behaviors …

Approach to reward is a fundamental adaptive behavior, disruption of which is a core
symptom of addiction and depression. Nucleus accumbens (NAc) dopamine is required for …

Rationale We recently found that muscarinic receptor (mAChR) stimulation in the ventral
tegmental area (VTA) is involved in the acquisition of a feeding task. Objective To investigate …

Rationale Stimulation of ventral tegmental area (VTA) muscarinic acetylcholine receptors
(mAChRs) is implicated in feeding. Objective To investigate the effects of mAChR blockade …

The dorsomedial striatum (DMS) has been strongly implicated in flexible, outcome‐based
decision making, including the outcome‐specific Pavlovian‐to‐instrumental transfer effect …

The high attrition rates for dietary interventions aimed at promoting a healthier body mass
may be caused, at least in part, by constant exposure to environmental stimuli that are …

Exposure to drug-associated cues evokes drug-seeking behavior and is regarded as a
major cause of relapse. Cues evoke burst firing of ventral tegmental area (VTA) dopamine …