The Wilms' tumor suppressor gene wt1 encodes a zinc‐finger transcription factor that plays
an important role in the development of the mammalian genitourinary system. Mutations in …

Wilms' tumor is a childhood kidney tumor that is a striking example of the way that cancer
may arise through development gone awry. A proportion of these tumors develop as a result …

The Wilms tumor protein WT1 is an essential factor for kidney development. In humans,
mutations in WT1 lead to Wilms tumor, a pediatric kidney cancer as well as to developmental …

Wilms' tumor (nephroblastoma) represents a unique example of an aberrant kidney
formation that can result from mutations in a tumor suppressor gene, Wilms' tumor 1 (WT1) …

The Wilms' tumour gene, WT1, encodes a zinc-finger transcription factor that is inactivated in
a subset of Wilms' tumours. Mutation analysis in human patients and genetic experiments in …

The human Wilms' tumor predisposition gene, WT1, is a Cys-His zinc finger polypeptide
which appears to be a transcription factor controlling gene expression during embryonic …

WT1 is a Wilms' tumor suppressor gene that maps to human chromosome 11p13 and
encodes a putative transcription factor implicated in controlling normal urogenital …

The Wilms' tumour suppressor gene, WT1, encodes multiple nuclear protein isoforms, all
containing four C-terminal zinc finger motifs. WT1 proteins can both activate and repress …

Wilms' tumour is a childhood kidney cancer, and a classic example of cancer arising through
disrupted development (Armstrong et al., 1992). It is one of the most common solid …

Mutations in the Wilms' tumor 1 gene, WT1, cause pediatric nephroblastoma and the severe
genitourinary disorders of Frasier and Denys-Drash syndromes. High levels of WT1 …