Elemental fingerprint as a cerebrospinal fluid biomarker for the diagnosis of Parkinson's disease

F Maass, B Michalke, A Leha, M Boerger… - Journal of …, 2018 - Wiley Online Library
The diagnosis of Parkinson's disease (PD) still lacks objective diagnostic markers
independent of clinical criteria. Cerebrospinal fluid (CSF) samples from 36 PD and 42 age …

[HTML][HTML] Elemental fingerprint: Reassessment of a cerebrospinal fluid biomarker for Parkinson's disease

F Maass, B Michalke, D Willkommen, A Leha… - Neurobiology of …, 2020 - Elsevier
The aim of the study was to validate a predictive biomarker machine learning model for the
classification of Parkinson's disease (PD) and age-matched controls (AMC), based on …

[HTML][HTML] Metallomic Biomarkers in Cerebrospinal fluid and Serum in patients with Parkinson's disease in Indian population

J Sanyal, SSSJ Ahmed, HKT Ng, T Naiya, E Ghosh… - Scientific reports, 2016 - nature.com
Parkinson's disease (PD) is a neurodegenerative disease with the absence of markers for
diagnosis. Several studies on PD reported the elements imbalance in biofluids as …

[HTML][HTML] Metallomic profiling and linkage map analysis of early Parkinson's disease: a new insight to aluminum marker for the possible diagnosis

SSSJ Ahmed, W Santosh - PloS one, 2010 - journals.plos.org
Background Parkinson's disease (PD) is the most common neurodegenerative disorder. The
diagnosis of PD is challenging and currently none of the biochemical tests have proven to …

Elemental profile of cerebrospinal fluid in patients with Parkinson's disease

A Alimonti, B Bocca, A Pino, F Ruggieri, G Forte… - Journal of Trace …, 2007 - Elsevier
To ascertain the potential role of chemical elements (namely, Al, Ba, Be, Bi, Ca, Cd, Co, Cr,
Cu, Fe, Hg, Li, Mg, Mn, Mo, Ni, Pb, Sb, Si, Sn, Sr, Tl, V, W, Zn and Zr) as markers in the …

Intelligent Identification of Cerebrospinal Fluid for the Diagnosis of Parkinson's Disease

H Chen, S Guo, Z Zhuang, S Ouyang, P Lin… - Analytical …, 2024 - ACS Publications
Cerebrospinal fluid (CSF) biomarkers are more sensitive than the Movement Disorder
Society (MDS) criteria for detecting prodromal Parkinson's disease (PD). Early detection of …

[HTML][HTML] Assessing plasma levels of selenium, copper, iron and zinc in patients of Parkinson's disease

HW Zhao, J Lin, XB Wang, X Cheng, JY Wang, BL Hu… - PloS one, 2013 - journals.plos.org
Trace elements have been recognized to play an important role in the development of
Parkinson's disease (PD). However, it is difficult to precisely identify the relationship …

[HTML][HTML] Interdependence of metals and its binding proteins in Parkinson's disease for diagnosis

A Anirudhan, P Prabu, J Sanyal, TK Banerjee… - npj Parkinson's …, 2021 - nature.com
Metalloproteins utilizes cellular metals which plays a crucial function in brain that linked with
neurodegenerative disorders. Parkinson's disease (PD) is a neurodegenerative disorder …

[HTML][HTML] Brain-biomarker changes in body fluids of patients with Parkinson's disease

C Cocco, AL Manai, E Manca, B Noli - International Journal of Molecular …, 2023 - mdpi.com
Parkinson's disease (PD) is an incurable neurodegenerative disease that is rarely
diagnosed at an early stage. Although the understanding of PD-related mechanisms has …

Characterizing iron deposition in Parkinson's disease using susceptibility-weighted imaging: an in vivo MR study

J Zhang, Y Zhang, J Wang, P Cai, C Luo, Z Qian, Y Dai… - Brain research, 2010 - Elsevier
Brain-iron deposition has been proposed to play an important role in the pathophysiology of
Parkinson's disease (PD). The aim of this study was to evaluate the feasibility of …