Quantitative magnetization transfer imaging for non‐contrast enhanced detection of myocardial fibrosis

K López, R Neji, A Bustin, I Rashid… - Magnetic …, 2021 - Wiley Online Library
Purpose To develop a novel gadolinium‐free model‐based quantitative magnetization
transfer (qMT) technique to assess macromolecular changes associated with myocardial …

Clinical Gadolinium-Free Magnetic Resonance Imaging With Magnetization Transfer Contrast Detects Cardiac Fibrosis With High Sensitivity and Specificity Compared …

TA Stromp, SW Leung, L Jing, BK Fornwalt, VL Sorrell… - Circulation, 2014 - Am Heart Assoc
Intro: Cardiac fibrosis identified by late gadolinium enhanced (LGE) cardiac MRI (CMR) is
prognostic of adverse cardiac events, but is contraindicated in high-risk patients with …

Non-contrast free breathing and motion corrected 3D whole heart quantitative magnetization transfer imaging for assessment of myocardial fibrosis

K Lopez, R Neji, R Mukherjee, J Whitaker, R Razavi… - 2017 - archive.ismrm.org
We have developed a contrast-free free-breathing motion corrected (100% scan efficiency)
3D whole heart imaging technique for measurement of myocardial magnetization transfer …

Non-contrast myocardial fibrosis imaging using MT-weighted balanced steady state free precession MRI

SW Leung, R Lawless, VL Sorrell… - Proc. Intl. Soc. Magn …, 2014 - archive.ismrm.org
The development of myocardial fibrosis significantly heightens the risk of sudden cardiac
death. Late gadolinium enhanced (LGE) MRI has become the reference standard for …

Quantification of myocardial fibrosis using noninvasive T2‐mapping magnetic resonance imaging: Preclinical models of aging and pressure overload

LE Lee, B Chandrasekar, P Yu, L Ma - NMR in Biomedicine, 2022 - Wiley Online Library
Noninvasive imaging of cardiac fibrosis is important for early diagnosis and intervention in
chronic heart diseases. Here, we investigated whether noninvasive, contrast agent‐free MRI …

Myocardial tissue characterization using magnetic resonance noncontrast t1 mapping in hypertrophic and dilated cardiomyopathy

S Dass, JJ Suttie, SK Piechnik, VM Ferreira… - Circulation …, 2012 - Am Heart Assoc
Background—Noncontrast magnetic resonance T1 mapping reflects a composite of both
intra-and extracellular signal. We hypothesized that noncontrast T1 mapping can …

[HTML][HTML] Detecting diffuse myocardial fibrosis with CMR: the future has only just begun

TD Karamitsos, S Neubauer - JACC: Cardiovascular Imaging, 2013 - jacc.org
The development of late gadolinium enhancement imaging (LGE) in the late 1990s
revolutionized the clinical application of cardiovascular magnetic resonance (CMR) in …

A non-contrast CMR index for assessing myocardial fibrosis

Q Yin, D Abendschein, D Muccigrosso… - Magnetic resonance …, 2017 - Elsevier
Purpose Safe, sensitive, and non-invasive imaging methods to assess the presence, extent,
and turnover of myocardial fibrosis are needed for early stratification of risk in patients who …

Histological validation of cardiac magnetic resonance analysis of regional and diffuse interstitial myocardial fibrosis

LM Iles, AH Ellims, H Llewellyn, JL Hare… - European Heart …, 2015 - academic.oup.com
Aim Myocardial fibrosis is fundamental in the pathogenesis of heart failure. Late gadolinium
enhancement (LGE) with cardiac magnetic resonance (CMR) imaging is commonly …

Endogenous assessment of diffuse myocardial fibrosis in patients with T‐mapping

JWM van Oorschot, F Güçlü, S de Jong… - Journal of Magnetic …, 2017 - Wiley Online Library
Purpose Recently, it was shown that a significantly higher T1ρ is found in compact
myocardial fibrosis after chronic myocardial infarction. In this study, we investigated the …