[HTML][HTML] A study of target effect sizes in randomised controlled trials published in the Health Technology Assessment journal
JC Rothwell, SA Julious, CL Cooper - Trials, 2018 - Springer
Background When designing a randomised controlled trial (RCT), an important
consideration is the sample size required. This is calculated from several components; one …
consideration is the sample size required. This is calculated from several components; one …
[HTML][HTML] Practical help for specifying the target difference in sample size calculations for RCTs: the DELTA2 five-stage study, including a workshop.
JA Cook, SA Julious, W Sones… - Health Technology …, 2019 - ncbi.nlm.nih.gov
BACKGROUND The randomised controlled trial is widely considered to be the gold
standard study for comparing the effectiveness of health interventions. Central to its design …
standard study for comparing the effectiveness of health interventions. Central to its design …
Role of feasibility and pilot studies in randomised controlled trials: a cross-sectional study
AJ Blatch-Jones, W Pek, E Kirkpatrick, M Ashton-Key - BMJ open, 2018 - bmjopen.bmj.com
Objectives To assess the value of pilot and feasibility studies to randomised controlled trials
(RCTs) funded by the National Institute for Health Research (NIHR) Health Technology …
(RCTs) funded by the National Institute for Health Research (NIHR) Health Technology …
The use of nonrandomized evidence to estimate treatment effects in health technology assessment
S Kent, M Salcher-Konrad, S Boccia… - Journal of …, 2021 - becarispublishing.com
Health technology assessment (HTA) is increasingly informed by nonrandomized studies,
but there is limited guidance from HTA bodies on expectations around evidence quality and …
but there is limited guidance from HTA bodies on expectations around evidence quality and …
[HTML][HTML] A reinvestigation of recruitment to randomised, controlled, multicenter trials: a review of trials funded by two UK funding agencies
Abstract Background Randomised controlled trials (RCTs) are the gold standard
assessment for health technologies. A key aspect of the design of any clinical trial is the …
assessment for health technologies. A key aspect of the design of any clinical trial is the …
[HTML][HTML] Assessing methods to specify the target difference for a randomised controlled trial: DELTA (Difference ELicitation in TriAls) review.
JA Cook, J Hislop, TE Adewuyi, K Harrild… - Health Technology …, 2014 - ncbi.nlm.nih.gov
BACKGROUND The randomised controlled trial (RCT) is widely considered to be the gold
standard study for comparing the effectiveness of health interventions. Central to the design …
standard study for comparing the effectiveness of health interventions. Central to the design …
The completeness of intervention descriptions in published National Institute of Health Research HTA-funded trials: a cross-sectional study
L Douet, R Milne, S Anstee, F Habens, A Young… - BMJ open, 2014 - bmjopen.bmj.com
Objectives The objective of this study was to assess whether National Institute of Health
Research (NIHR) Health Technology Assessment (HTA)-funded randomised controlled trials …
Research (NIHR) Health Technology Assessment (HTA)-funded randomised controlled trials …
Influence of reported study design characteristics on intervention effect estimates from randomised controlled trials: combined analysis of meta-epidemiological …
The design of randomised controlled trials (RCTs) should incorporate characteristics (such
as concealment of randomised allocation and blinding of participants and personnel) that …
as concealment of randomised allocation and blinding of participants and personnel) that …
[HTML][HTML] Using systematic reviews to inform NIHR HTA trial planning and design: a retrospective cohort
S Bhurke, A Cook, A Tallant, A Young… - BMC medical research …, 2015 - Springer
Abstract Background Chalmers and Glasziou's paper published in 2014 recommends
research funding bodies should mandate that proposals for additional primary research are …
research funding bodies should mandate that proposals for additional primary research are …
A systematic review of comparisons of effect sizes derived from randomised and non-randomised studies.
RR MacLehose, BC Reeves, IM Harvey… - Health technology …, 2000 - europepmc.org
Background There is controversy about the value of evidence about the effectiveness of
healthcare interventions from non-randomised study designs. Advocates for quasi …
healthcare interventions from non-randomised study designs. Advocates for quasi …