Cold shock domain (CSD)‐containing proteins have been found in all three domains of life
and function in a variety of processes that are related, for the most part, to post …

YB-1 is a member of the numerous families of proteins with an evolutionary ancient cold-
shock domain. It is involved in many DNA-and RNA-dependent events and regulates gene …

The highly conserved grp78 core promoter element plays an important role in the induction
of grp78 under diverse stress signals. Previous studies have established a functional region …

The microenvironment of the cancer cell is pivotal to its phenotypic regulation. One of the
central components of the microenvironment is temperature. An elevation in environmental …

Hsp27 and clusterin (CLU are stress-activated small heat shock proteins that are up-
regulated in many cancers where they play important roles in stress-induced protein …

Under cell stress, global protein synthesis is inhibited to preserve energy. One mechanism is
to sequester and silence mRNAs in ribonucleoprotein complexes known as stress granules …

Extracellular cell stress proteins are highly conserved phylogenetically and have been
shown to act as powerful signalling agonists and receptors for selected ligands in several …

Compared to bacteria and plants, the cold shock response has attracted little attention in
mammals except in some areas such as adaptive thermogenesis, cold tolerance, storage of …

Expression of the Y-box protein YB-1 is increased in proliferating normal and cancer cells,
but its role in cell proliferation and cell cycle progression is unclear. We have identified a cell …

Cold‐inducible RNA binding protein (CIRP) was discovered after the cells were exposed to
a moderate cold shock because its production was induced. Other cellular stresses such as …