The interaction between the brain and the gut has been recognized for many centuries. This
bidirectional interaction occurs via neural, immunological and hormonal routes, and is …

The luminal-mucosal interface of the intestinal tract is the first relevant location where
microorganism-derived antigens and all other potentially immunogenic particles face the …

The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

Communication between the brain and gut is not one-way, but a bidirectional highway
whereby reciprocal signals between the two organ systems are exchanged to coordinate …

Objective Emerging preclinical evidence has shown that the bidirectional signaling between
the gastrointestinal (GI) tract and the brain, the so-called gut-brain axis, plays an important …

Over the past few years, scientific interest in the gut–brain axis (ie, the bidirectional
communication system between the gastrointestinal tract and the brain) has exploded …

Background: Interactions between brain and gut have been suspected for centuries but our
understanding of the neural centers and neurohormonal links that establish bidirectional …

The existence of a bidirectional communication system termed the “gut-brain axis” linking
the gastrointestinal tract with the brain has been recognized since the nineteenth century. In …

Functional gastrointestinal disorders (FGIDs), characterized by chronic abdominal
complaints without a structural or biochemical cause, are common diseases that are …

The gut-brain axis describes a bidirectional interplay within the enteric environment between
the intestinal epithelium, the mucosal immune system, and the microbiota with the enteric …