The indole nucleus is an important element of many natural and synthetic molecules with
significant biological activity. This review covers some of the relevant and recent …

Prevention, accurate diagnosis, and effective treatment of infections are the main challenges
in the overall management of infectious diseases. The best example is the ongoing SARs …

Indoles are a significant heterocyclic system in natural products and drugs. They are
important types of molecules and natural products and play a main role in cell biology. The …

Indole represents one of the most important privileged scaffolds in drug discovery. Indole
derivatives have the unique property of mimicking the structure of peptides and to bind …

Introduction Indolizines are structural isomers with indoles. Although several indole-based
commercial drugs are available in the market, none of the indolizine-based drugs are …

Indoles are amongst the most essential class of heteroaromatics in organic chemistry, being
commonly found in biologically active natural products. Indole and its derivatives have …

Indole‐containing compounds demonstrate an array of biological activities relevant to
numerous human diseases. The biological activities of diverse indole‐based agents are …

New types of antidiabetic agents are continually needed with diabetes becoming the
epidemic in the world. Indole alkaloids play an important role in natural products owing to …

Cancer, which is the uncontrolled growth of cells, is the second leading cause of death after
heart disease. Targeting drugs, especially to specific genes and proteins involved in growth …

Heterocyclic moiety serve as perfect framework on which pharmacophores can be effectively
attached to produce novel drugs. Among various heterocyclic compounds, nitrogen-based …