Molecular initiating events of the intersex phenotype: Low-dose exposure to 17α-ethinylestradiol rapidly regulates molecular networks associated with gonad …
Intersex, or the presence of oocytes in the testes, has been documented in fish following
exposure to wastewater effluent and estrogenic compounds. However, the molecular …
exposure to wastewater effluent and estrogenic compounds. However, the molecular …
Transcriptomic analysis identifies early cellular and molecular events by which estrogen disrupts testis differentiation and causes feminization in Xenopus laevis
Y Li, Y Shen, J Li, M Cai, Z Qin - Aquatic toxicology, 2020 - Elsevier
Extensive studies have shown that estrogenic endocrine-disrupting chemicals (EDCs) can
disrupt testis differentiation and even cause feminization in vertebrates. However, little is …
disrupt testis differentiation and even cause feminization in vertebrates. However, little is …
[HTML][HTML] Testis transcriptome alterations in zebrafish (Danio rerio) with reduced fertility due to developmental exposure to 17α-ethinyl estradiol
T Porseryd, NR Caspillo, K Volkova, L Elabbas… - General and …, 2018 - Elsevier
Abstract 17α-Ethinylestradiol (EE 2) is a ubiquitous aquatic contaminant shown to decrease
fish fertility at low concentrations, especially in fish exposed during development. The …
fish fertility at low concentrations, especially in fish exposed during development. The …
Environmental estrogens suppress hormones, behavior, and reproductive fitness in male fathead minnows
D Martinović, WT Hogarth, RE Jones… - … and Chemistry: An …, 2007 - Wiley Online Library
This study explored the possibility that environmental estrogens in sewage effluent may
reduce the reproductive fitness of adult male fish by suppressing their reproductive …
reduce the reproductive fitness of adult male fish by suppressing their reproductive …
Feminization, altered gonadal development, and liver damage in least killifish (Heterandria formosa) exposed to sublethal concentrations of 17α-ethinylestradiol
LM Jackson, BE Felgenhauer, PL Klerks - … and environmental safety, 2019 - Elsevier
The widespread use of the synthetic estrogen 17 α-ethinylestradiol (EE 2) has resulted in
elevated levels in aquatic environments, where it is known to act as an endocrine disrupting …
elevated levels in aquatic environments, where it is known to act as an endocrine disrupting …
Aneuploid sperm formation in rainbow trout exposed to the environmental estrogen 17α-ethynylestradiol
KH Brown, IR Schultz, JG Cloud… - Proceedings of the …, 2008 - National Acad Sciences
Environmental contaminants that mimic native estrogens (ie, environmental estrogens) are
known to significantly impact a wide range of vertebrate species and have been implicated …
known to significantly impact a wide range of vertebrate species and have been implicated …
A computational model of the hypothalamic-pituitary-gonadal axis in male fathead minnows exposed to 17α-ethinylestradiol and 17β-estradiol
KH Watanabe, Z Li, KJ Kroll, DL Villeneuve… - Toxicological …, 2009 - academic.oup.com
Estrogenic chemicals in the aquatic environment have been shown to cause a variety of
reproductive anomalies in fish including full sex reversal, intersex, and altered population …
reproductive anomalies in fish including full sex reversal, intersex, and altered population …
Lack of a heritable reproductive defect in the offspring of male rainbow trout exposed to the environmental estrogen 17α-ethynylestradiol
Endocrine disruptors, including environmental estrogens, have been shown to induce
heritable effects through both genetic and epigenetic mechanisms in mammals. Despite this …
heritable effects through both genetic and epigenetic mechanisms in mammals. Despite this …
Molecular signaling pathways elicited by 17α-ethinylestradiol in Japanese medaka male larvae undergoing gonadal differentiation
Estrogenic contaminants released into water bodies are potentially affecting the
reproduction of aquatic organisms. Exposure to 17α-ethinylestradiol (EE2), a synthetic …
reproduction of aquatic organisms. Exposure to 17α-ethinylestradiol (EE2), a synthetic …
Anchoring ethinylestradiol induced gene expression changes with testicular morphology and reproductive function in the medaka
HD Miller, BW Clark, DE Hinton, A Whitehead… - PLoS …, 2012 - journals.plos.org
Environmental estrogens are ubiquitous in the environment and can cause detrimental
effects on male reproduction. In fish, a multitude of effects from environmental estrogens …
effects on male reproduction. In fish, a multitude of effects from environmental estrogens …