Physiological insights of exercise hyperventilation in arterial and chronic thromboembolic pulmonary hypertension

S Farina, N Bruno, C Agalbato, M Contini… - International journal of …, 2018 - Elsevier
Background Pulmonary hypertension (PH) patients show, during exercise, an excessive
increase in ventilation (VE) compared to carbon dioxide output (VCO 2), determining a high …

[HTML][HTML] Clinical usefulness of end-tidal CO2 profiles during incremental exercise in patients with chronic thromboembolic pulmonary hypertension

RP Ramos, EVM Ferreira, FM Valois, A Cepeda… - Respiratory …, 2016 - Elsevier
Introduction Great ventilation to carbon dioxide output (Δ V˙ E/Δ V˙ CO 2) and reduced end-
tidal partial pressures for CO 2 (P et CO 2) during incremental exercise are hallmarks of …

Exercise pathophysiology in patients with primary pulmonary hypertension

XG Sun, JE Hansen, RJ Oudiz, K Wasserman - Circulation, 2001 - Am Heart Assoc
Background Patients with primary pulmonary hypertension (PPH) have a pulmonary
vasculopathy that leads to exercise intolerance due to dyspnea and fatigue. To better …

Effect of normobaric hypoxia on exercise performance in pulmonary hypertension: randomized trial

SR Schneider, LC Mayer, M Lichtblau, C Berlier… - Chest, 2021 - Elsevier
Background Many patients with pulmonary arterial or chronic thromboembolic pulmonary
hypertension (PH) wish to travel to altitude or by airplane, but their risk of hypoxia-related …

Gas exchange and ventilatory efficiency during exercise in pulmonary vascular diseases

J Weatherald, A Boucly, D Montani, X Jaïs… - Archivos de …, 2020 - Elsevier
Abstract Background and Objective Ventilatory inefficiency (high V′ E/V′ CO 2) and
resting hypocapnia are common in pulmonary vascular disease and are associated with …

Oxygen uptake is more efficient in idiopathic pulmonary arterial hypertension than in chronic thromboembolic pulmonary hypertension

X Shi, J Guo, S Gong, R Sapkota, W Yang, H Liu… - …, 2016 - Wiley Online Library
Background and objective The responses of oxygen uptake efficiency (OUE) during
cardiopulmonary exercise training (CPET) have not been reported in patients with …

Effects of exercise and vasodilators on cerebral tissue oxygenation in pulmonary hypertension

S Müller-Mottet, FF Hildenbrand, S Keusch, E Hasler… - Lung, 2015 - Springer
Background Arterial and thromboembolic pulmonary hypertension (PH) lead to arterial
hypoxaemia. Objective To investigate whether cerebral tissue oxygenation (CTO) in patients …

End-tidal PCO2 abnormality and exercise limitation in patients with primary pulmonary hypertension

Y Yasunobu, RJ Oudiz, XG Sun, JE Hansen… - Chest, 2005 - Elsevier
Objectives Primary pulmonary hypertension (PPH) is a pulmonary vasculopathy resulting in
exercise intolerance, usually due to dyspnea. We hypothesized that ventilation is increased …

Pulmonary hypertension and ventilation during exercise: Role of the pre-capillary component

S Caravita, A Faini, G Deboeck, A Bondue… - The Journal of Heart and …, 2017 - Elsevier
Background Excessive exercise-induced hyperventilation and high prevalence of exercise
oscillatory breathing (EOB) are present in patients with post-capillary pulmonary …

The lowest VE/VCO2 ratio best identifies chronic thromboembolic pulmonary hypertension

Q Xi, Z Zhao, Z Liu, X Ma, Q Luo, W Liu - Thrombosis research, 2014 - Elsevier
Introduction The natural history of acute pulmonary embolism (PE) under treatment is about
a gradual resolution of the thrombi, and uncommonly, the development of chronic …